Document Detail

A review and meta-analysis of studies on the effect and timing of β-blocker administration in patients with ST-segment elevation myocardial infarction.
MedLine Citation:
PMID:  21068528     Owner:  NLM     Status:  MEDLINE    
The utility of β-blockers during an evolving ST-segment elevation myocardial infarction (STEMI) has substantial theoretic physiological backing. This coupled with early successes using β-blockers in STEMI promulgated multiple guidelines expanding the use of this class of medication to all patients with acute coronary syndromes. However, recent studies have questioned the utility of β-blockers in the emergency department in these patients. The purpose of this article is to review the evidence behind the use of β-blockers in the emergency department for STEMI patients.
Lorenzo Paladino; Richard Sinert; Ethan Brandler
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Review    
Journal Detail:
Title:  Hospital practice (1995)     Volume:  38     ISSN:  2154-8331     ISO Abbreviation:  Hosp Pract (1995)     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-11     Completed Date:  2010-12-30     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  101268948     Medline TA:  Hosp Pract (1995)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  63-8     Citation Subset:  AIM; IM    
Deparmtent of Emergency Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, USA.
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MeSH Terms
Administration, Oral
Adrenergic beta-Antagonists / pharmacology,  therapeutic use*
Drug Administration Schedule
Drug Therapy, Combination
Emergency Medicine / methods*
Emergency Treatment / methods*
Evidence-Based Medicine
Hospital Mortality
Infusions, Intravenous
Myocardial Infarction / diagnosis,  drug therapy*,  mortality
Odds Ratio
Patient Selection
Practice Guidelines as Topic
Research Design
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Adrenergic beta-Antagonists

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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