Document Detail

Review of the literature: Treatment of dyspigmentation with fractionated resurfacing.
MedLine Citation:
PMID:  20698875     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Traditional ablative laser resurfacing is associated with adverse side effects, including prolonged erythema, edema, burning, milia, acne, crusting, and hypo- and hyperpigmentation. Fractional photothermolysis (FP) has been introduced to overcome the disadvantages of traditional ablative and nonablative resurfacing. With FP, the microscopic, pixilated pattern of wounding in the dermis results in significant skin pigmentary and textural improvements without the adverse effects of prolonged wound healing and risks of dyspigmentation associated with traditional ablative resurfacing. FP has been reported to improve hypo- and hyperpigmentation in a variety of cutaneous conditions.
OBJECTIVE: To review the dermatologic literature on the use of FP for treatment of dyspigmentation.
RESULTS: Review of the Medline literature identified 35 studies on treatment of cutaneous conditions associated with dyspigmentation with ablative FP (AFP) and nonablative FP (NAFP). Specifically, we found treatment of melasma, postinflammatory hyperpigmentation, nevus of Ota, hypo- and hyperpigmented scars, poikiloderma of Civatte, laser-induced hypo- and hyperpigmentation, and dyschromia associated with photoaging.
CONCLUSIONS: AFP and NAFP are potentially effective modalities for the treatment of dyspigmentation of the face and neck. The authors have indicated no significant interest with commercial supporters.
Emily P Tierney; C William Hanke
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  36     ISSN:  1524-4725     ISO Abbreviation:  Dermatol Surg     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-29     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1499-508     Citation Subset:  IM    
Copyright Information:
© 2010 by the American Society for Dermatologic Surgery, Inc.
Laser and Skin Surgery Center of Indiana, Carmel, Indiana, USA.
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MeSH Terms
Cicatrix / etiology,  prevention & control
Erythema / etiology,  prevention & control
Laser Therapy / adverse effects,  methods
Phototherapy / methods*
Pigmentation Disorders / pathology,  physiopathology,  therapy*
Reconstructive Surgical Procedures / adverse effects,  methods
Skin / pathology,  physiopathology
Skin Aging
Surface Properties
Wound Healing
Comment In:
Dermatol Surg. 2010 Oct;36(10):1509   [PMID:  20698874 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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