| Reversible splenial lesion syndrome in cerebral malaria. | |
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MedLine Citation:
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PMID: 20381148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 71-year-old Caucasian man living in Congo was investigated by serial magnetic resonance imaging (MRI) after having presented cerebral malaria due to Plasmodium falciparum. The clinical picture was characterized initially by coma and seizures. The patient developed multiple organ failure. There was, at 4 months follow-up only, a minimal neurological improvement consistent with minimally conscious state. The first cerebral MRI on day 17 showed a lesion of the splenium of corpus callosum with high signal intensity on DWI and FLAIR sequence and reduced ADC, and small cortical infarcts in the internal occipital regions. Follow-up MRI obtained 36 days later showed a complete resolution of splenial lesion, though without clinical improvement. Cerebral malaria should be added to the list of possible causes of reversible lesion of the splenium of corpus callosum. |
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Authors:
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P Hantson; D Hernalsteen; G Cosnard |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-04-08 |
Journal Detail:
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Title: Journal of neuroradiology. Journal de neuroradiologie Volume: 37 ISSN: 0150-9861 ISO Abbreviation: J Neuroradiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-05 Completed Date: 2011-01-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705086 Medline TA: J Neuroradiol Country: France |
Other Details:
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Languages: eng Pagination: 243-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Department of Intensive Care, cliniques universitaires Saint-Luc, université catholique de Louvain, Brussels, Belgium. philippe.hantson@uclouvain.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antimalarials / therapeutic use Corpus Callosum / pathology* Humans Magnetic Resonance Imaging Malaria, Cerebral / pathology*, therapy Male Quinine / therapeutic use Renal Dialysis Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antimalarials; 130-95-0/Quinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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