Document Detail


Reversible renin-dependent renovascular hypertension successfully treated with percutaneous transluminal renal angioplasty and stenting.
MedLine Citation:
PMID:  15876819     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 37-year old woman was suspected of having renovascular hypertension because of recent onset severe hypertension (blood pressure 220/135 mmHg; compared to 132/65 mmHg two years earlier) and an abdominal bruit. A captopril renal scan indicated the presence of right renal artery stenosis. Additionally, a captopril plasma renin activity (PRA) provocation test showed a positive result for renovascular hypertension (baseline PRA = 291 microU/mL; 1 hour post-captopril PRA = 1444 microU/mL). Selective renal angiography demonstrated a severe critical stenotic lesion at the distal portion of the right renal artery. Blood pressure (BP) decreased to 136/80 mmHg one day after successful percutaneous transluminal renal angioplasty and stenting. Repeat renal angiography six months after the procedure revealed no evidence of in-stent restenosis. Blood pressure (BP = 137/76 mmHg) and plasma renin profile (baseline PRA = 23.8 microU/mL; 1 hour post-captopril PRA=22.3 microu/mL) also were normal six months following initial revascularization. Moreover, blood pressure (137/84 mmHg) and renin profile remained normal 2.5 years after the procedure (baseline PRA = 24.3 microU/mL; 1 hour post-captopril = 25.6 microU/mL). The results of this study have thus demonstrated a case of renin-dependent renovascular hypertension in which both the blood pressure and plasma renin activity profile normalized following successful percutaneous transluminal angioplasty and stenting.
Authors:
Ber-Ren Fang; Chin-Yew Lin
Related Documents :
508019 - Short-term therapy of severe hypertension. hemodynamic correlates of the antihypertensi...
6367489 - Comparison of renin-specific igg and antibody fragments in studies of blood pressure re...
10052739 - Effectiveness of 1,25-dihydroxyvitamin d supplementation on blood pressure reduction in...
3014909 - Acth, cortisol, and renin responses to arterial hypotension in sheep.
2409359 - Vasodilatation of small and large arteries in hypertension.
1071589 - Exchangeable sodium in experimental hypertension in rats.
6269679 - Captopril and the maintenance of blood pressure after sinoaortic denervation in the rab...
5545119 - Influence of scar on left ventricular performance at the onset of myocardial ischemia: ...
15828959 - Penile erectile responses to electric stimulation are enhanced by a new phosphodiestera...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International heart journal     Volume:  46     ISSN:  1349-2365     ISO Abbreviation:  -     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-05-06     Completed Date:  2005-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244240     Medline TA:  Int Heart J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  339-45     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Angioplasty, Balloon / methods*
Female
Humans
Hypertension, Renovascular / blood,  therapy*
Renal Artery / radiography
Renal Artery Obstruction / complications,  radiography
Renin / blood*
Stents*
Chemical
Reg. No./Substance:
EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ventriculatrial block during atrioventricular nodal reentrant tachycardia suggesting existence of an...
Next Document:  Congenital solitary kidney with renovascular hypertension diagnosed by means of captopril-enhanced r...