| Reversible renin-dependent renovascular hypertension successfully treated with percutaneous transluminal renal angioplasty and stenting. | |
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MedLine Citation:
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PMID: 15876819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 37-year old woman was suspected of having renovascular hypertension because of recent onset severe hypertension (blood pressure 220/135 mmHg; compared to 132/65 mmHg two years earlier) and an abdominal bruit. A captopril renal scan indicated the presence of right renal artery stenosis. Additionally, a captopril plasma renin activity (PRA) provocation test showed a positive result for renovascular hypertension (baseline PRA = 291 microU/mL; 1 hour post-captopril PRA = 1444 microU/mL). Selective renal angiography demonstrated a severe critical stenotic lesion at the distal portion of the right renal artery. Blood pressure (BP) decreased to 136/80 mmHg one day after successful percutaneous transluminal renal angioplasty and stenting. Repeat renal angiography six months after the procedure revealed no evidence of in-stent restenosis. Blood pressure (BP = 137/76 mmHg) and plasma renin profile (baseline PRA = 23.8 microU/mL; 1 hour post-captopril PRA=22.3 microu/mL) also were normal six months following initial revascularization. Moreover, blood pressure (137/84 mmHg) and renin profile remained normal 2.5 years after the procedure (baseline PRA = 24.3 microU/mL; 1 hour post-captopril = 25.6 microU/mL). The results of this study have thus demonstrated a case of renin-dependent renovascular hypertension in which both the blood pressure and plasma renin activity profile normalized following successful percutaneous transluminal angioplasty and stenting. |
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Authors:
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Ber-Ren Fang; Chin-Yew Lin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: International heart journal Volume: 46 ISSN: 1349-2365 ISO Abbreviation: - Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-05-06 Completed Date: 2005-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101244240 Medline TA: Int Heart J Country: Japan |
Other Details:
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Languages: eng Pagination: 339-45 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angioplasty, Balloon / methods* Female Humans Hypertension, Renovascular / blood, therapy* Renal Artery / radiography Renal Artery Obstruction / complications, radiography Renin / blood* Stents* |
| Chemical | |
Reg. No./Substance:
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EC 3.4.23.15/Renin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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