| Reversible obesity and plasma fat metabolites. | |
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MedLine Citation:
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PMID: 6836044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rats were made to overeat and gain weight (about 50 g) by long-acting protamine zinc insulin (PZI) treatment. When the PZI treatment was stopped, the rats ate much less than normal for at least seven days. During recovery from PZI-induced obesity, negative correlations were observed between food intake and plasma levels of the fat metabolites, free fatty acids, glycerol, and ketone bodies. A similar but smaller effect was observed during recovery from dietary obesity (about 15 g). The plasma fat metabolites may be the blood-borne signals which suppress hunger under these conditions. |
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Authors:
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R G Carpenter; S P Grossman |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Physiology & behavior Volume: 30 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1983 Jan |
Date Detail:
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Created Date: 1983-05-27 Completed Date: 1983-05-27 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 51-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight* / drug effects Eating / drug effects Fatty Acids, Nonesterified / blood Glycerol / blood Insulin, Long-Acting / pharmacology Ketone Bodies / blood Lipids / blood* Lipolysis / drug effects Male Rats Rats, Inbred Strains |
| Grant Support | |
ID/Acronym/Agency:
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AM 25245/AM/NIADDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Nonesterified; 0/Insulin, Long-Acting; 0/Ketone Bodies; 0/Lipids; 56-81-5/Glycerol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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