Document Detail

Reversible myocardial dysfunction: basics and evaluation.
MedLine Citation:
PMID:  15561318     Owner:  NLM     Status:  MEDLINE    
Large areas of non-functional but viable myocardium with reversible dysfunction are commonly seen in patients with acute myocardial infarction. Both reperfusion of acutely ischemic myocardium and chronic myocardial ischemia may produce a reversible forms of ventricular dysfunction. The two main conditions that lead to reversible myocardial dysfunction are stunned myocardium and hibernating myocardium. Myocardial stunning represents post-ischemic myocardial dysfunction that persists despite restoration of normal flow, with gradual return of contractile function. Hibernating myocardium is a state of persistently impaired myocardial function at rest due to reduced coronary blood flow owing to residual stenosis that can be restored toward normal by revascularization. The success of the revascularization procedures depends on the presence of amount of dysfunctional but viable myocardium. The basics and evaluation of reversible myocardial dysfunction are reviewed.
Ramesh M Gowda; Ijaz A Khan; Balendu C Vasavada; Terrence J Sacchi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of cardiology     Volume:  97     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-24     Completed Date:  2005-08-16     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  349-53     Citation Subset:  IM    
Division of Cardiology, Long Island College Hospital, Brooklyn, NY, USA.
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MeSH Terms
Coronary Circulation / physiology
Heart / physiopathology*
Myocardial Contraction / physiology
Myocardial Stunning / physiopathology

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