Document Detail


Reversible leukoencephalopathy in cerebral amyloid angiopathy presenting as subacute dementia.
MedLine Citation:
PMID:  12099917     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report concerns a 71-year-old woman who had rapid progressive dementia along with myocloni and increased blood pressure. Cranial computed tomography and magnetic resonance imaging scans showed bilateral widespread white matter changes with mass effect. A brain biopsy revealed an amyloid angiopathy in leptomeningeal as well as cerebral cortex arteries. After 2 months of antihypertensive treatment, a dramatic improvement of cognitive functions and a spectacular regression of leukoencephalopathy were observed. We suggest that hypertensive encephalopathy may worsen or reveal cerebral amyloid angiopathy.
Authors:
M Sarazin; P Amarenco; J Mikol; D Dimitri; G Lot; M G Bousser
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of neurology : the official journal of the European Federation of Neurological Societies     Volume:  9     ISSN:  1351-5101     ISO Abbreviation:  Eur. J. Neurol.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-07-08     Completed Date:  2002-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9506311     Medline TA:  Eur J Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  353-8     Citation Subset:  IM    
Affiliation:
Service de Neurologie, Hôpital Bichat, Paris, France. marie.sarazin@brt.ap-hop-paris.fr
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MeSH Terms
Descriptor/Qualifier:
Aged
Anticonvulsants / therapeutic use
Antihypertensive Agents / therapeutic use*
Biopsy
Brain / pathology
Cerebral Amyloid Angiopathy / complications,  drug therapy*,  pathology*
Dementia / drug therapy*,  etiology,  pathology*
Female
Humans
Hypertension / complications,  drug therapy,  pathology
Magnetic Resonance Imaging
Nerve Fibers / pathology
Chemical
Reg. No./Substance:
0/Anticonvulsants; 0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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