Document Detail


Reversible left ventricular dysfunction (takotsubo cardiomyopathy) with deep negative T waves due to possible cardiac sympathetic denervation.
MedLine Citation:
PMID:  15729419     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of characteristic left ventricular contraction disorder representing takotsubo cardiomyopathy after exercise is reported. A 58-year-old Japanese woman with no history of cardiac disease was admitted for chest oppression after exercise. A diagnosis of myocardial infarction was suspected because of her symptom, and the electrocardiographic and echocardiographic findings. Coronary angiography revealed normal arteries, while left ventriculography demonstrated asynergy with apical akinesis and basal hyperkinesis. Deep negative T waves were observed on the electrocardiogram on the second hospital day and sustained for over a month. Repeated measurements of heart rate viability and 123I-metaiodobenzylguanidine scintigraphy showed transient dysfunction of the cardiac autonomic nervous system. From these findings, it was concluded that cardiac autonomic denervation plays a pivotal role in the etiology of takotsubo cardiomyopathy.
Authors:
Yuji Yamamoto; Yoshihiro J Akashi; Hiroaki Yamaguchi; Harumizu Sakurada; Masayasu Hiraoka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  21     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-24     Completed Date:  2005-05-03     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  181-4     Citation Subset:  IM    
Affiliation:
Tokyo Metropolitan Hiroo General Hospital, Tokyo, Japan. yyam-tky@umin.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Cardiomyopathies / diagnosis*,  physiopathology*
Electrocardiography
Exercise / physiology*
Female
Heart / innervation*
Heart Rate / physiology
Humans
Middle Aged
Sympathetic Nervous System / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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