Document Detail

Reversible left ventricular apical ballooning associated with jet lag in a Taiwanese woman: A case report.
MedLine Citation:
PMID:  22477274     Owner:  NLM     Status:  In-Data-Review    
Reversible left ventricular apical ballooning, without coronary artery stenosis, is a novel heart syndrome mimicking acute myocardial infarction, and is very rare in Taiwan. A 74-year-old Taiwanese woman returned from travelling abroad for one week and suffered from persistent, severe jet lag with sleep disturbance. She had a cold exacerbated by bronchial asthma for three days. She presented with sudden onset of chest pain after drinking three cups of coffee and taking a sauna for more than 1 h. On admission, an electrocardiogram showed ST segment elevation in leads II, III, aVF and V(3-6), and cardiac enzyme tests revealed minimal elevation. An echocardiogram showed apical ballooning and basal hyperkinesias of the left ventricle (LV) in systole. A coronary angiogram on the second day was normal, while the ST segment was still elevated, and the patient continued to experience chest pain. A negative T wave developed three days later. The electrocardiogram abnormality and LV dysfunction resolved completely six months later. A takotsubo (ampulla) cardiomyopathy was diagnosed. The activated myocardial adrenergic nervous system, stimulated by acute and marked stress in this patient, with more adrenergic innervations distributed in the apex of the LV, may be the trigger for this novel cardiac syndrome.
Nen-Chung Chang; Mei-Shu Lin; Chun-Yao Huang; Chun-Ming Shih; Wei-Fung Bi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of angiology : official publication of the International College of Angiology, Inc     Volume:  16     ISSN:  1061-1711     ISO Abbreviation:  Int. J. Angiol.     Publication Date:  2007  
Date Detail:
Created Date:  2012-04-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504821     Medline TA:  Int J Angiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  62-5     Citation Subset:  -    
Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital.
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