| Reversible fetal hydrops associated with indomethacin use. | |
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MedLine Citation:
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PMID: 11770593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Ductus arteriosus constriction is a known complication of exposure to indomethacin in utero. Nonimmune hydrops associated with indomethacin use has been reported in only six cases, all twins over 32 weeks' gestation. CASE: We present a case of fetal hydrops associated with tricuspid regurgitation and ductal constriction developing within 30 hours of instituting indomethacin tocolysis in a 28-week singleton gestation. Discontinuation of indomethacin resulted in partial resolution of these findings 72 hours later. A normal infant was delivered subsequently. CONCLUSION: Ultrasonographic screening for signs of constriction of the ductus arteriosus should be done within 48 hours of instituting indomethacin therapy at any gestational age. |
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Authors:
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L Pratt; J Digiosia; J N Swenson; B Trampe; C B Martin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 90 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1997 Oct |
Date Detail:
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Created Date: 2001-12-27 Completed Date: 2002-01-14 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 676-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Wisconsin-Madison, 53715, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ductus Arteriosus / drug effects Female Humans Hydrops Fetalis / chemically induced*, ultrasonography Indomethacin / adverse effects* Pregnancy Time Factors Tocolytic Agents / adverse effects* Tricuspid Valve Insufficiency / chemically induced Ultrasonography, Prenatal |
| Chemical | |
Reg. No./Substance:
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0/Tocolytic Agents; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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