| Reversible diastolic dysfunction after successful coronary artery bypass surgery. Assessment by transesophageal Doppler echocardiography. | |
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MedLine Citation:
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PMID: 7956385 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the potential effects of coronary artery bypass surgery on left ventricular diastolic filling, 12 patients, aged 65 +/- 11 years, were studied by serial transesophageal Doppler echocardiograms. Doppler measures of mitral inflow velocity were made before, immediately after, 4 h after, and 20 h after cardiopulmonary bypass (CPB). Left atrial pressure was directly measured and controlled at 10 +/- 2 mm Hg for each study period. Mitral maximal early inflow velocity (E)/maximal atrial velocity (A) ratios and atrial filling fractions were calculated as indexes of diastolic function from maximal E and A velocities and their time velocity integrals, respectively. Data sets were available for serial comparison in 11 patients and were also compared with an age-matched control group of normal values. The results of E/A ratios were as follows: control group--1.4 +/- 0.2; before CPB--1.7 +/- 0.6; immediately after CPB--1.0 +/- 0.2 (p < 0.05 vs control group, before CPB, and 20 h after CPB values); 4 h after CPB--0.8 +/- 0.2 (p < 0.05 vs control group, before CPB, and 20 h after CPB values); and 20 h after CPB--1.3 +/- 0.4. Atrial filling fractions were as follows: control group--0.29 +/- 0.05; before CPB--0.25 +/- 0.06; immediately after CPB--0.43 +/- 0.07 (p < 0.05 vs control group, before CPB, and 20 h after CPB values); 4 h after CPB, 0.46 +/- 0.07 (p < 0.05 vs control group, before CPB, and 20 h after CPB values); and 20 h after CPB--0.35 +/- 0.06. Alterations in Doppler indexes of left ventricular filling occurred immediately after CPB and persisted 4 h after CPB. These indexes returned to baseline values by 20 h after CPB. This suggests reversible diastolic dysfunction in patients after coronary artery bypass surgery. |
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Authors:
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J Gorcsan; P Diana; J Lee; W E Katz; B G Hattler |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Chest Volume: 106 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1994 Nov |
Date Detail:
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Created Date: 1994-12-09 Completed Date: 1994-12-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1364-9 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiology, University of Pittsburgh Medical Center 15261. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Coronary Artery Bypass* Diastole Echocardiography, Transesophageal* / instrumentation, methods, statistics & numerical data Female Hemodynamics Humans Male Middle Aged Postoperative Complications / physiopathology, ultrasonography* Posture / physiology Surgical Procedures, Elective Time Factors Ventricular Dysfunction, Left / physiopathology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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