| Reversible defects on myocardial perfusion imaging early after coronary stent implantation: a predictor of late restenosis. | |
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MedLine Citation:
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PMID: 18338236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: If coronary artery was treated with optimal stent implantation, myocardial perfusion in the territory supplied by a dilated coronary artery should be not reversible. However, several studies have demonstrated reversible perfusion in the territory supplied by a coronary artery with an optimally implanted stent. The main objective of this study was to evaluate the incidence of reversible defects detected by M-SPECT early after optimal PTCA with stent implantation. Its second objective was to determine the predictive value of detecting reversible defects after stent implantation for late restenosis. METHODS: About 66 patients that underwent M-SPECT within 24 h of successful PTCA with stent implantation were included. All patients were followed up clinically and angiographically. The incidence of reversible perfusion defects on M-SPECT and the rate of late restenosis in target coronary arteries were evaluated retrospectively. RESULTS: Reversible perfusion defects on M-SPECT were observed in 26% of the patients and in 36% of lesions following successful PTCA with stent implantation. The incidence of late restenosis was significantly higher in patients and lesions with reversible perfusion defects (47% vs. 18%). According to binary logistic regression analysis, the presence of a reversible perfusion defects was the only independent predictor of late restenosis. |
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Authors:
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Dae-Weung Kim; Soon-Ah Park; Chang-Guhn Kim; Cheol Lee; Seok Kyu Oh; Jin-Won Jeong |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-03-13 |
Journal Detail:
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Title: The international journal of cardiovascular imaging Volume: 24 ISSN: 1569-5794 ISO Abbreviation: Int J Cardiovasc Imaging Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-08 Completed Date: 2008-07-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100969716 Medline TA: Int J Cardiovasc Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 503-10 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Wonkwang University School of Medicine, 344-2 Shinyong-Dong, Iksan, Jeollabuk-do 570-711, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary / adverse effects, instrumentation* Coronary Angiography Coronary Circulation* Coronary Restenosis / etiology*, physiopathology, radionuclide imaging Coronary Stenosis / physiopathology, radionuclide imaging*, therapy Female Humans Logistic Models Male Middle Aged Organophosphorus Compounds / diagnostic use* Organotechnetium Compounds / diagnostic use* Predictive Value of Tests Radiopharmaceuticals / diagnostic use* Retrospective Studies Risk Assessment Stents* Tomography, Emission-Computed, Single-Photon* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Organophosphorus Compounds; 0/Organotechnetium Compounds; 0/Radiopharmaceuticals; 0/technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane |
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