Document Detail


Reversible cerebral vasoconstriction syndrome associated with autonomic dysreflexia.
MedLine Citation:
PMID:  20186562     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 32-year-old man with a residual spastic quadriparesis from a traumatic C5-C6 fracture experienced a severe thunderclap headache. The medical history revealed an episode of autonomic dysreflexia (AD) due to neurogenic bladder/urinary tract infection (UTI). Blood pressure monitoring at admission revealed hypertension; blood pressure reaching 160/100 mmHg (average blood pressure in these patients and also in this patient being 90/60 mmHg). CT scan of the head, cerebrospinal fluid examination, CT angiography and MR angiography of the brain vessels were normal. Another UTI and a subsequent spell of AD were diagnosed. The patient continued to experience recurrent thunderclap headaches. Selective catheter cerebral angiography revealed multiple calibre changes in the intracranial blood vessels. A diagnosis of reversible cerebral vasoconstriction syndrome (RCVS) due to AD was considered. A magnetic resonance imaging (MRI) of the brain after 2 weeks revealed ischaemic changes in the left hemisphere. Follow-up brain MRI after 3 weeks showed reduction in size of the ischaemic changes, and catheter angiography after 6 weeks demonstrated improvement/normalization. A diagnosis of RCVS could be established. Repeated MRI/CT of the brain after 6 months demonstrated a large infarction in the left hemisphere. RCVS has been reported to occur in various clinical settings. It can occur in the setting of AD in patients with traumatic cervical cord injury. Prompt recognition of RCVS may be of vital importance to avoid further morbidity in patients with spinal cord injury.
Authors:
Bengt Edvardsson; Staffan Persson
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-02-26
Journal Detail:
Title:  The journal of headache and pain     Volume:  11     ISSN:  1129-2377     ISO Abbreviation:  J Headache Pain     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-08-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100940562     Medline TA:  J Headache Pain     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  277-80     Citation Subset:  IM    
Affiliation:
Department of Neurology, Faculty of Neurology, Lund University Hospital, 221 85 Lund, Sweden. Bengt.Edvardsson@med.lu.se
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MeSH Terms
Descriptor/Qualifier:
Adult
Autonomic Dysreflexia / etiology*,  physiopathology
Brain Infarction / etiology,  pathology,  physiopathology
Cerebral Arteries / pathology,  physiopathology,  radiography
Cervical Vertebrae / injuries
Early Diagnosis
Headache Disorders, Primary / etiology*,  physiopathology
Humans
Magnetic Resonance Imaging
Male
Quadriplegia / complications,  physiopathology
Spinal Cord Injuries / complications*,  physiopathology
Spinal Fractures / complications
Urinary Bladder, Neurogenic / complications,  physiopathology
Urinary Tract Infections / complications,  physiopathology
Vasospasm, Intracranial / etiology*,  physiopathology

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