Document Detail


Reversible acute leukoencephalopathy as a form of presentation in cerebral amyloid angiopathy.
MedLine Citation:
PMID:  19853861     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Cerebral amyloid angiopathy (CAA) may present as cerebral haemorrhage, cerebral infarction and periventricular white matter lesions. Reversible leukoencephalopathy is a rare manifestation of CAA. AIMS OF THE STUDY: To describe two patients with reversible acute leukoencephalopathy as the first manifestation of CAA. PATIENTS: Two consecutive patients were admitted to our neurology department with transient focal neurological symptoms. They showed reversible focal leukoencephalopathy on magnetic resonance imaging (MRI). CAA was finally diagnosed in both, and pathologically confirmed in one. The latter patient showed multiple foci of petechial bleeding in the cortex and subcortex in T2-weighted GRE sequences, suggestive of CAA. CONCLUSION: Reversible acute focal leukoencephalopathy may be an infrequent clinical and radiological pattern of CAA.
Authors:
L M Cano; S Mart?nez-Y?lamos; C Maj?s; M A Albert?; S Boluda; R Velasco; F Rubio
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-23
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  288     ISSN:  1878-5883     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  190-3     Citation Subset:  IM    
Affiliation:
Department of Neurology, Hospital Universitari de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain. lcano@bellvitgehospital.cat
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Aged
Brain / pathology*
Brain Edema / etiology,  pathology
Cerebral Amyloid Angiopathy / pathology*
Fatal Outcome
Female
Headache / etiology,  pathology
Humans
Ischemic Attack, Transient / etiology,  pathology
Magnetic Resonance Imaging
Male
Middle Aged
Tomography, X-Ray Computed

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