| Reversible Symptomatic Myocarditis Induced by All-Trans Retinoic Acid Administration during Induction Treatment of Acute Promyelocytic Leukemia: Rare Cardiac Manifestation as a Retinoic Acid Syndrome. | |
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MedLine Citation:
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PMID: 21860725 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Treatment by All-trans retinoic acid (ATRA) followed by anthracycline-AraC chemotherapy has improved the outcome of acute promyelocytic leukemia. ATRA is usually well tolerated, but a few major side effects can be observed. Retinoic acid syndrome (RAS) often occurs during the induction chemotherapy of acute promyelocytic leukemia. A pericardial effusion is a common cardiac manifestation but myocarditis has been rarely documented. Here we reports a very rare case of fully recovered myocarditis as a result of RAS related to ATRA administration during induction treatment of acute promyelocytic leukemia which documented by echocardiographic evidence. |
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Authors:
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Seonghoon Choi; Hyeong-Su Kim; Chang-Soo Jung; Seong-Woong Jung; Yun-Ja Lee; Jin-Kyeong Rheu; Jung-Rae Jo; Nam-Ho Lee |
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Publication Detail:
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Type: Journal Article Date: 2011-06-30 |
Journal Detail:
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Title: Journal of cardiovascular ultrasound Volume: 19 ISSN: 2005-9655 ISO Abbreviation: J Cardiovasc Ultrasound Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-08-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101477138 Medline TA: J Cardiovasc Ultrasound Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 95-8 Citation Subset: - |
Affiliation:
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Division of Cardiology, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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