| Reversible MRI lesions after seizures. | |
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MedLine Citation:
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PMID: 9203254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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After generalized or partial seizures, transient lesions may appear on magnetic resonance (MR) images. The mechanisms of MR changes might be a defect in cerebral autoregulation and blood-brain permeability. We report a patient with partial and secondary generalized tonic-clonic seizures. After her first seizure which was generalized tonic-clonic in nature, we detected multiple high signal intensities over the frontal cortical area on proton density images which were enhanced with gadolinium on T1-weighted images. The first and repeated EEGs showed no abnormalities or epileptic discharges. We started carbamezapine (600 mg/d) and excluded systemic diseases like vasculitis, infections, aetiological factors causing cerebrovascular diseases. In the follow-up, she was seizure free under antiepileptic therapy and no other neurological deficit. Repeated MR scans after 24 months from her first seizure revealed no pathologic signal intensities. Although the pathophysiology is unknown, recognition of reversible lesions helps diagnostic and therapeutic approaches to abnormal MR findings after seizures. |
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Authors:
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C Aykut-Bingol; S Tekin; D Ince; S Aktan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Seizure : the journal of the British Epilepsy Association Volume: 6 ISSN: 1059-1311 ISO Abbreviation: Seizure Publication Date: 1997 Jun |
Date Detail:
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Created Date: 1997-08-29 Completed Date: 1997-08-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9306979 Medline TA: Seizure Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 237-9 Citation Subset: IM |
Affiliation:
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Department of Neurology, Marmara University School of Medicine, Istanbul, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticonvulsants / therapeutic use Carbamazepine / therapeutic use Cerebral Cortex / pathology* Epilepsy / diagnosis*, drug therapy Female Frontal Lobe / pathology* Humans Magnetic Resonance Imaging Seizures / diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 298-46-4/Carbamazepine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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