Document Detail


Reversible Horner's syndrome and dysthyroid ocular myopathy associated with Hashimoto's disease.
MedLine Citation:
PMID:  14636849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although it has been frequently stated that thyroid disease induces Horner's syndrome, there have been few reports describing the anatomical relation of goiter to the cervical preganglionic sympathetic nerve fibers in acquired Horner's syndrome, which is identified by the eye-drop test for adrenergic sensitivity. CASE: A 40-year-old woman with Hashimoto's disease presented with vertical diplopia, and blepharoptosis and miosis on the left side. OBSERVATIONS: Computed tomography scan showed hypertrophy of the right inferior rectus muscle, which resulted from a dysthyroid process, causing the limitation of upward movement of the right eye. The eye-drop test for adrenergic sensitivity revealed that only the left pupil dilated significantly after administration of 5% tyramine, and the Mueller's muscle on the left side did not respond. These results suggest that Horner's syndrome was due to a preganglionic sympathetic lesion. Magnetic resonance imaging (MRI) of the neck showed chronic inflammatory lesions in both lobes of the thyroid gland identified by a high-intensity signal. CONCLUSION: The reconstruction technique of MRI demonstrated that the swollen left lobe of the thyroid gland was compressing the pathway of the cervical preganglionic sympathetic nerve fibers.
Authors:
Tamami Okamoto; Manabu Kase; Masahiko Yokoi; Yasuo Suzuki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Japanese journal of ophthalmology     Volume:  47     ISSN:  0021-5155     ISO Abbreviation:  Jpn. J. Ophthalmol.     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2003-11-25     Completed Date:  2004-02-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0044652     Medline TA:  Jpn J Ophthalmol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  587-90     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Teine Keijin-kai Hospital, Sapporo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anisocoria / etiology
Blepharoptosis / etiology
Diplopia / etiology
Female
Horner Syndrome / complications*,  physiopathology*
Humans
Magnetic Resonance Imaging
Muscular Diseases / etiology*,  physiopathology,  radiography
Oculomotor Muscles* / radiography
Recovery of Function
Thyroiditis, Autoimmune / diagnosis,  etiology*
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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