| Reversible cytotoxic edema in a cirrhotic patient following TIPS. | |
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MedLine Citation:
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PMID: 19344367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors report the magnetic resonance imaging (MRI) findings in a 52-year-old man with cirrhosis from chronic hepatitis C who developed episodic acute hepatic encephalopathy Type C following placement of transjugular intrahepatic portosystemic shunt (TIPS). Brain MRI revealed hyperintense T2 signal and restricted diffusion distributed through the cerebral cortex. The patient's mentation improved with treatment of his hyperammonemia. Brain MRI performed 5 months later revealed diffuse cerebral atrophy and new areas of hyperintense T2 signal in the cerebral white matter. The cortical signal abnormalities and low apparent diffusion coefficient values on the initial MRI resolved with exception of a mild amount of hyperintense FLAIR signal in the cingulate cortex. Acute hepatic encephalopathy following portosystemic shunting -- either from placement of TIPS or from development of spontaneous shunts -- is a widely recognized complication of portal hypertension and cirrhosis. We report MRI findings of reversible cytotoxic edema in a patient with acute hepatic encephalopathy following placement of TIPS. |
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Authors:
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James R Babington; Justin H Stahl; David L Coy |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-03-24 |
Journal Detail:
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Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: 19 ISSN: 1552-6569 ISO Abbreviation: J Neuroimaging Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-30 Completed Date: 2009-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: United States |
Other Details:
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Languages: eng Pagination: 391-3 Citation Subset: IM |
Affiliation:
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Department of Graduate Medical Education, Virginia Mason Medical Center, Seattle, WA 98111, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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pathology* Brain Edema / etiology*, pathology* Chronic Disease Hepatitis C / complications Humans Liver Cirrhosis / etiology, pathology*, therapy Magnetic Resonance Imaging Male Middle Aged Portasystemic Shunt, Transjugular Intrahepatic / adverse effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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