| Reversibility of cytotoxic edema in tacrolimus leukoencephalopathy. | |
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MedLine Citation:
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PMID: 20933182 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Posterior reversible encephalopathy syndrome, a serious neurotoxicity, may develop rarely in patients receiving tacrolimus. Because the underlying etiology of posterior reversible encephalopathy syndrome is vasogenic edema, it is generally accepted to be a reversible neurologic condition. Cranial magnetic resonance imaging techniques enable detection of the type of edema, and they are widely used in the differential diagnosis and prognostic prediction of posterior reversible encephalopathy syndrome. Presented here is a case of posterior reversible encephalopathy syndrome in which the patient recovered completely, despite radiologic findings indicating the coexistence of vasogenic and cytotoxic edema secondary to tacrolimus therapy after liver transplantation. |
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Authors:
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Sanem Yilmaz; Sarenur Gokben; Cigdem Arikan; Cem Calli; Gul Serdaroglu |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 43 ISSN: 1873-5150 ISO Abbreviation: Pediatr. Neurol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-11 Completed Date: 2011-02-10 Revised Date: 2011-03-15 |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 359-62 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Child Neurology, Department of Pediatrics, Ege University, Bornova-Izmir, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain Edema
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chemically induced* Child Diffusion Magnetic Resonance Imaging / methods Hepatitis B, Chronic / complications Humans Immunosuppressive Agents / adverse effects* Leukoencephalopathies / chemically induced*, pathology Liver Failure, Acute / drug therapy, etiology, surgery Liver Transplantation / methods Male Tacrolimus / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents; 109581-93-3/Tacrolimus |
| Comments/Corrections | |
Comment In:
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Pediatr Neurol. 2011 Mar;44(3):236; author reply 236
[PMID:
21310344
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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