Document Detail


Reversed-phase high-performance liquid chromatographic measurement of the P-aminobenzoic acid synthesized by Streptococcus sanguis.
MedLine Citation:
PMID:  10557192     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study investigated the biosynthesis of P-aminobenzoic acid by Streptococcus sanguis and the role of P-aminobenzoic acid in the interaction between Streptococcus sanguis and Streptococcus mutans. METHODS: A reversed-phase high-performance liquid chromatographic technique was used to analyze the P-aminobenzoic acid synthesized by Streptococcus sanguis in an anaerobic atmosphere. RESULTS: The results showed, that (1) the chromatographic method established in this study had good linear relation and the average recovery of P-aminobenzoic acid was 80%, and (2) Streptococcus sanguis did synthesize P-aminobenzoic acid, and the mean concentration of P-aminobenzoic acid was 1.23 micrograms/mL. CONCLUSIONS: The results of this study will help further studies of the factors that may have effects on P-aminobenzoic acid synthesis by Streptococcus sanguis and on the role of P-aminobenzoic acid in the microbial homeostasis of dental plaque.
Authors:
X D Zhou; T Hu; P Zhang; H Tan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)     Volume:  1     ISSN:  1462-6446     ISO Abbreviation:  Chin J Dent Res     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1999-11-17     Completed Date:  1999-11-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100892845     Medline TA:  Chin J Dent Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  37-40     Citation Subset:  D    
Affiliation:
College of Stomatology, West China University of Medical Sciences, Chengdu, P. R. China.
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MeSH Terms
Descriptor/Qualifier:
4-Aminobenzoic Acid / analysis,  metabolism*
Chromatography, High Pressure Liquid / methods
Dental Plaque / microbiology*
Ecosystem
Streptococcus mutans / metabolism
Streptococcus sanguis / metabolism*
Chemical
Reg. No./Substance:
150-13-0/4-Aminobenzoic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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