Document Detail


Reverse redistribution of thallium-201 detected by SPECT imaging after dipyridamole in angina pectoris.
MedLine Citation:
PMID:  2337025     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reverse redistribution refers to a thallium-201 perfusion defect that develops or becomes more evident on delayed imaging compared with the initial image immediately after stress. To determine the diagnostic importance of reverse redistribution after intravenous dipyridamole, thallium-201 single photon emission computed tomography and quantitative coronary arteriography were performed in 90 men with angina pectoris. Of the 250 myocardial segments analyzed, reverse redistribution was present in 17 (7%). Minimal coronary cross-sectional area in proximal vessel segments was less than or equal to 2.0 mm2 more often in regions with transient perfusion abnormalities than in regions with reverse redistribution (66 vs 29%, p less than 0.05). Compared with regions exhibiting transient perfusion abnormalities, regions with reverse redistribution had larger proximal arterial diameters (1.9 +/- 1.1 vs 1.3 +/- 1.1 mm, p less than 0.001) and cross-sectional areas (3.9 +/- 3.1 vs 2.2 +/- 2.6 mm2, p less than 0.001). Coronary artery dimensions and relative stenosis severity did not differ between those regions with normal perfusion and those with reverse redistribution. Reverse redistribution detected by thallium-201 single photon emission computed tomographic imaging after dipyridamole is uncommon, appears to occur as frequently in normal subjects as in patients undergoing coronary arteriography and does not indicate the presence of severe coronary artery disease.
Authors:
J J Popma; T C Smitherman; B S Walker; T R Simon; G J Dehmer
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  65     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-13     Completed Date:  1990-06-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1176-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Dallas Veterans Administration Medical Center, Texas.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angina Pectoris / physiopathology,  radiography,  radionuclide imaging*
Coronary Angiography
Coronary Circulation* / drug effects
Dipyridamole / pharmacology*
Humans
Male
Middle Aged
Thallium Radioisotopes / diagnostic use*,  pharmacokinetics
Tomography, Emission-Computed, Single-Photon*
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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