Document Detail

Reversal of prolonged suxamethonium apnoea with fresh frozen plasma in a 6-week-old infant.
MedLine Citation:
PMID:  1781528     Owner:  NLM     Status:  MEDLINE    
A period of apnoea lasting 480 minutes following suxamethonium in a 6-week-old male infant is described. Neuromuscular function recovered following the administration of fresh frozen plasma. The infant was found to be homozygous for atypical cholinesterase (E1a E1a). This is believed to be the youngest reported case of suxamethonium apnoea.
R S Gill; N O'Connell; R P Scott
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  46     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-03-12     Completed Date:  1992-03-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1036-8     Citation Subset:  AIM; IM    
Department of Anaesthesia, Odstock Hospital, Salisbury, Wiltshire.
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MeSH Terms
Apnea / chemically induced*,  enzymology,  therapy
Cholinesterases / genetics
Succinylcholine / adverse effects*
Time Factors
Reg. No./Substance:
306-40-1/Succinylcholine; EC
Comment In:
Anaesthesia. 1992 Jul;47(7):630   [PMID:  1626690 ]

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