| Reversal of exercise-induced hemodynamic and electrocardiographic abnormalities after coronary artery bypass surgery. | |
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MedLine Citation:
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PMID: 6977419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Forty patients (35 men and five women) who experienced hypotension during maximal symptom-limited exercise test were retested after a 12 +/- 4-month interval. Mean age was 53.5 years. All patients had multiple-vessel disease. Seventeen patients underwent coronary artery bypass surgery because of disabling angina, and 23 patients without disabling angina continued under medical management. At entry, there were no significant differences in age, left ventricular function or exercise performance between the medical and surgical groups. At follow-up, the surgical group showed an average increase in the exercise duration of 2.2 +/- 1.7 minutes (p less than 0.001), maximal heart rate of 17 +/- 15 beats/min (p less than 0.001), maximal systolic blood pressure of 26 +/- 23 mm Hg (p less than 0.001) and maximal rate-pressure product of 60 +/- 41 (p less than 0.001). These measurements did not change significantly in the medically managed group. Exercise-induced hypotension is apparently caused by ischemic left ventricular dysfunction, since in the majority of patients, it is reversible after successful revascularization. This observation is supported by the lack of improvement in a comparable group of patients managed without surgery. |
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Authors:
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R J Sarma; M E Sanmarco |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Circulation Volume: 65 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1982 Apr |
Date Detail:
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Created Date: 1982-05-21 Completed Date: 1982-05-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 684-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / etiology Antihypertensive Agents / therapeutic use Blood Pressure / drug effects Coronary Angiography Coronary Artery Bypass* Coronary Disease / surgery* Exercise Test* Female Heart Rate / drug effects Hemodynamics* / drug effects Humans Male Middle Aged Physical Fitness Propranolol / therapeutic use Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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