Document Detail

Reversal of exercise-induced hemodynamic and electrocardiographic abnormalities after coronary artery bypass surgery.
MedLine Citation:
PMID:  6977419     Owner:  NLM     Status:  MEDLINE    
Forty patients (35 men and five women) who experienced hypotension during maximal symptom-limited exercise test were retested after a 12 +/- 4-month interval. Mean age was 53.5 years. All patients had multiple-vessel disease. Seventeen patients underwent coronary artery bypass surgery because of disabling angina, and 23 patients without disabling angina continued under medical management. At entry, there were no significant differences in age, left ventricular function or exercise performance between the medical and surgical groups. At follow-up, the surgical group showed an average increase in the exercise duration of 2.2 +/- 1.7 minutes (p less than 0.001), maximal heart rate of 17 +/- 15 beats/min (p less than 0.001), maximal systolic blood pressure of 26 +/- 23 mm Hg (p less than 0.001) and maximal rate-pressure product of 60 +/- 41 (p less than 0.001). These measurements did not change significantly in the medically managed group. Exercise-induced hypotension is apparently caused by ischemic left ventricular dysfunction, since in the majority of patients, it is reversible after successful revascularization. This observation is supported by the lack of improvement in a comparable group of patients managed without surgery.
R J Sarma; M E Sanmarco
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  65     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-05-21     Completed Date:  1982-05-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  684-9     Citation Subset:  AIM; IM    
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MeSH Terms
Angina Pectoris / etiology
Antihypertensive Agents / therapeutic use
Blood Pressure / drug effects
Coronary Angiography
Coronary Artery Bypass*
Coronary Disease / surgery*
Exercise Test*
Heart Rate / drug effects
Hemodynamics* / drug effects
Middle Aged
Physical Fitness
Propranolol / therapeutic use
Retrospective Studies
Reg. No./Substance:
0/Antihypertensive Agents; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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