Document Detail


[Revealing dacryoadenitis inflammation as Wegener's granulomatosis].
MedLine Citation:
PMID:  16050415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Wegener's granulomatosis is a necrotizing granulomatous vasculitis characterized by the involvement of the upper airways, lungs and kidneys.
CASE REPORT: A 39-year-old man presented with a 8-month history of proptosis of left eye. He had a history of recuring sinusitis and dyspnea. The diagnosis of Wegener's granulomotosis was confirmed by the nasal biopsy. A complete remission was achieved after treatment with corticosteroids, cyclophosphamide and trimethoprine sulfamethoxazole.
COMMENTS AND CONCLUSION: Wegener's granulomatosis is a multisystemic inflammatory disease of unknown origin. The classic diagnostic triad of this disease is necrotizing granuloma of the upper or lower respiratory tract, vasculitis and nephritis. The disease is usually fatal if untreated. However, early diagnosis and immunosuppressives such as cyclophosphamide can induce long term remission.
Authors:
S Tachfouti; N Boutimzine; O Cherkaoui; Z Bencherif; Z Dahreddine Mohcine
Publication Detail:
Type:  Case Reports; English Abstract; Journal Article    
Journal Detail:
Title:  Bulletin de la Société belge d'ophtalmologie     Volume:  -     ISSN:  0081-0746     ISO Abbreviation:  Bull Soc Belge Ophtalmol     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-29     Completed Date:  2005-10-26     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  7505353     Medline TA:  Bull Soc Belge Ophtalmol     Country:  Belgium    
Other Details:
Languages:  fre     Pagination:  7-12     Citation Subset:  IM    
Affiliation:
Service d'Ophtalmologie A, Hôpital des Spécialités, Rabat, Maroc. s_tachfouti@hotmail.com
Vernacular Title:
Dacryoadénite inflammatoire révélatrice d'une granulomatose de Wegener.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Cyclophosphamide / therapeutic use
Dacryocystitis / etiology*
Drug Combinations
Exophthalmos / etiology*
Humans
Male
Nasal Mucosa / pathology*
Sulfadiazine / therapeutic use
Trimethoprim / therapeutic use
Wegener Granulomatosis / complications*,  diagnosis*,  drug therapy
Chemical
Reg. No./Substance:
0/Drug Combinations; 39474-58-3/sulfadiazine, trimethoprim drug combination; 50-18-0/Cyclophosphamide; 68-35-9/Sulfadiazine; 738-70-5/Trimethoprim

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