| Revalidation of the Score for Neonatal Acute Physiology in the Vermont Oxford Network. | |
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MedLine Citation:
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PMID: 17158947 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Our specific objectives were (1) to document the performance of the revised Score for Neonatal Acute Physiology and the revised Score for Neonatal Acute Physiology Perinatal Extension in predicting death in the Vermont Oxford Network, compared with published normative values; (2) to determine whether this performance could be improved through recalibration of the weights for individual score items; (3) to determine the impact of including congenital anomalies in the predictive model; and (4) to compare performance against that of the Vermont Oxford Network risk adjustment, separately and in combination. METHODS: Fifty-eight Vermont Oxford Network centers collected data prospectively for the revised Score for Neonatal Acute Physiology in the first 12 hours after admission of infants in 2002. RESULTS: Data were collected for 10,469 infants, and analyses were undertaken for 9897 who met inclusion criteria. The median revised Score for Neonatal Acute Physiology was 5, and the mean birth weight was 1951 g. Recalibration of the revised Score for Neonatal Acute Physiology and revised Score for Neonatal Acute Physiology Perinatal Extension resulted in minimal changes in their discriminatory abilities. The Vermont Oxford Network risk adjustment performed similarly, compared with the revised Score for Neonatal Acute Physiology Perinatal Extension. CONCLUSIONS: Current score performance was similar to that observed previously, which suggests that the revised Score for Neonatal Acute Physiology and revised Score for Neonatal Acute Physiology Perinatal Extension have not decalibrated over the 7 years since the first cohort was assembled, despite advances in neonatal care during that period. Addition of congenital anomalies to the revised Score for Neonatal Acute Physiology Perinatal Extension improved discrimination significantly, particularly for infants with birth weights of >1500 g. The Vermont Oxford Network risk adjustment performed similarly, compared with the revised Score for Neonatal Acute Physiology Perinatal Extension. |
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Authors:
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John A F Zupancic; Douglas K Richardson; Jeffrey D Horbar; Joseph H Carpenter; Shoo K Lee; Gabriel J Escobar; |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Validation Studies Date: 2006-12-11 |
Journal Detail:
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Title: Pediatrics Volume: 119 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-03 Completed Date: 2007-01-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: United States |
Other Details:
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Languages: eng Pagination: e156-63 Citation Subset: AIM; IM |
Affiliation:
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Department of Neonatology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Rose Building, Room 318, Boston, MA 02215, USA. jzupanci@bidmc.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Apgar Score Birth Weight* Congenital Abnormalities / mortality Humans Infant Mortality* Infant, Newborn Intensive Care Units, Neonatal Predictive Value of Tests ROC Curve Severity of Illness Index* |
| Comments/Corrections | |
Comment In:
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Pediatrics. 2007 Jun;119(6):1246-7; author reply 1247
[PMID:
17545399
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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