Document Detail


Reusable, compression-sealed fluid cells for surface mounting to planar substrates.
MedLine Citation:
PMID:  19417916     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have developed a universal structure and mechanism for the repeatable, rapid-attachment of a fluid cell to a planar substrate. The fluid cell and all fluidic connections are completely contained in a plastic body such that attachment requires neither adhesives nor modification of the substrate. The geometry of the fluid cell is defined by the active area of the planar substrate (e.g. a sensor array). All required components have been quickly prototyped using Computer Numerical Control (CNC) machining. It is also straight-forward to create an array of fluid cells to attach to a single substrate (e.g. a standard microscope slide). All components are easy to assemble and can be cleaned and reused, making this flexible approach applicable for a wide range of lab-on-a-chip applications.
Authors:
Cy R Tamanaha; Michael P Malito; Shawn P Mulvaney; Lloyd J Whitman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2009-02-27
Journal Detail:
Title:  Lab on a chip     Volume:  9     ISSN:  1473-0197     ISO Abbreviation:  Lab Chip     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-06     Completed Date:  2009-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  England    
Other Details:
Languages:  eng     Pagination:  1468-71     Citation Subset:  IM    
Affiliation:
Naval Research Laboratory, Washington, DC 20375-5342, USA. cy.tamanaha@nrl.navy.mil
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MeSH Terms
Descriptor/Qualifier:
Equipment Design
Equipment Reuse
Microfluidic Analytical Techniques / instrumentation*
Oligonucleotide Array Sequence Analysis
Pressure
Surface Plasmon Resonance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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