Document Detail

Return to play? Athletes with congenital long QT syndrome.
MedLine Citation:
PMID:  23193325     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Competitive sports participation for athletes with congenital long QT syndrome (LQTS) is guided by the 2005 36th Bethesda Conference and the 2005 European Society of Cardiology (ESC) guidelines. The purpose of this study was to determine the prevalence and outcomes of patients with LQTS who chose to remain athletes following their diagnosis.
METHODS: Records of all patients between 6 and 40 years of age who were first evaluated in Mayo Clinic's LQTS Clinic from July 2000 to November 2010 were reviewed, for documentation of athletic participation after LQTS diagnosis and LQTS-related events during follow-up. Average follow-up was 5.5±3.4 years.
RESULTS: The cohort included 353 patients with LQTS (199 females, mean age 17±11 years, mean QTc 472±42 ms), of whom 182 had LQT1, 130 had LQT2, 37 had LQT3 and 4 had multiple LQTS mutations. The majority of patients (223, 63%) were either not involved in sports (88%) or chose to discontinue sports (12%) following evaluation. 130 patients (37%, 60 females, mean age 11±7 years, mean QTc 471±46 ms) remained in competitive athletics, including 20 with implantable cardioverter defibrillators (ICDs). Of these 130, 70 (54%) were genotype-positive/phenotype-negative and competing contrary to ESC guidelines but within the Bethesda guidelines. None of these athletes had a sport-related event. Of the 60 LQTS athletes continuing in sports contrary to both the Bethesda and ESC guidelines (genotype-positive/phenotype-positive), only one had a sporting-related event with appropriate ICD shock.
CONCLUSIONS: Athletes and their families are fully capable of self-disqualification. Among those athletes with LQTS who chose to remain in competitive sports, a low rate of cardiac events and no deaths were observed in over 650 athlete-years of follow-up. Current guideline-based recommendations for disqualification may be excessive for this disease.
Jonathan N Johnson; Michael J Ackerman
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Publication Detail:
Type:  Journal Article     Date:  2012-11-28
Journal Detail:
Title:  British journal of sports medicine     Volume:  47     ISSN:  1473-0480     ISO Abbreviation:  Br J Sports Med     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-17     Completed Date:  2013-05-17     Revised Date:  2014-08-19    
Medline Journal Info:
Nlm Unique ID:  0432520     Medline TA:  Br J Sports Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  28-33     Citation Subset:  IM    
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MeSH Terms
Exercise Test
Long QT Syndrome / congenital*,  diagnosis,  rehabilitation
Practice Guidelines as Topic
Recovery of Function
Retrospective Studies
Sports Medicine / methods*
Young Adult
Comment In:
Br J Sports Med. 2014 Aug;48(15):1135-6   [PMID:  23729177 ]
Br J Sports Med. 2013 Jan;47(1):4-5   [PMID:  23235963 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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