Document Detail


Return of fertility after autologous stem cell transplantation.
MedLine Citation:
PMID:  11821109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study cases where bone marrow transplantation (BMT) or peripheral blood stem cell transplantation (PBSCT)-induced menopause was entirely reversed. DESIGN: Retrospective analysis. SETTING: An inpatient BMT unit and an ambulatory fertility center in a university hospital. PATIENT(S): Two patients with Hodgkin's disease and two with advanced breast carcinoma requiring stem cell transplantation. INTERVENTION(S): Estrogen treatment, monitoring of follicle-stimulating hormone (FSH) and estradiol (E(2)) levels, and, ultimately, monitoring of pregnancy. MAIN OUTCOME MEASURE(S): Pregnancy. RESULT(S): All four patients established pregnancies, but two of them elected to terminate due to the use of tamoxifen early in pregnancy. CONCLUSION(S): Menopausal changes resulting from BMT may spontaneously reverse, with reestablishment of normal hormonal function and viable pregnancies.
Authors:
Avner Hershlag; Michael W Schuster
Related Documents :
8501179 - An aggressive philosophy in controlled ovarian stimulation cycles increases pregnancy r...
16954409 - Comparison of different gonadotrophin preparations in intrauterine insemination cycles ...
3556619 - Prediction of ovulation with the use of oral and vaginal electrical measurements during...
9797109 - Apoptotic cell death in human granulosa-lutein cells: a possible indicator of in vitro ...
20138269 - An ongoing pregnancy from two waves of follicles developing during a long follicular ph...
20540669 - Impact of female and male obesity on ivf/icsi: results of 700,000 art-cycles in germany.
21934699 - Relationship between body-mass index and serum folate concentrations in pregnant women.
3748379 - Histochemical demonstration of a concomitant reduction in neural vasoactive intestinal ...
9422019 - Fetal fibronectin, endotoxin, bacterial vaginosis and cervical length as predictors of ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  77     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-01-31     Completed Date:  2002-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  419-21     Citation Subset:  IM    
Affiliation:
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, North Shore University Hospital-New York University School of Medicine, 300 Community Drive, Manhasset, NY 11030, USA. ahershlag@nshs.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Antineoplastic Agents, Hormonal / adverse effects,  therapeutic use
Bone Marrow Transplantation / physiology*
Breast Neoplasms / therapy
Carcinoma, Ductal, Breast / therapy
Female
Fertility / physiology*
Hematopoietic Stem Cell Transplantation*
Hodgkin Disease / therapy
Hormone Replacement Therapy
Humans
Male
Pregnancy
Retrospective Studies
Tamoxifen / adverse effects,  therapeutic use
Chemical
Reg. No./Substance:
0/Antineoplastic Agents, Hormonal; 10540-29-1/Tamoxifen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Familial oligoasthenoteratozoospermia: evidence of autosomal dominant inheritance with sex-limited e...
Next Document:  Development of a protocol for determination of domoic acid in the sand crab (Emerita analoga): a pos...