Document Detail

Retrospective study: the presence of Malassezia in feline skin biopsies. A clinicopathological study.
MedLine Citation:
PMID:  11896965     Owner:  NLM     Status:  MEDLINE    
Malassezia spp. dermatitis, a rare disorder in cats, has previously been associated with immune suppression and internal malignancies. This study evaluates the presence and importance of Malassezia spp. in feline biopsy specimens submitted for histopathological examination. Five hundred and fifty haematoxylin and eosin-stained skin biopsy specimens received for histopathological examination between January 1999 and November 2000 were reviewed. Fifteen (2.7%) submissions contained Malassezia organisms in the stratum corneum of the epidermis or follicular infundibulum. Eleven of 15 cats presented with an acute onset of multifocal to generalized skin lesions. All 11 cats were euthanized or died within 2 months of the onset of clinical signs. Seven cats had dermatopathological changes and clinical signs supportive of paraneoplastic alopecia, and three cats had an interface dermatitis suggestive of erythema multiforme or thymoma-associated dermatosis. Histopathological changes were nonspecific in one cat that was euthanized 2 weeks following onset of severe pruritus and alopecia. In three cats, Malassezia spp. were found in localized sites (two chin, one footpads) and appeared inconsequential to their overall health status. One cat had Malassezia spp. in association with cutaneous demodicosis. These findings suggest that Malassezia yeast in dermatopathological specimens from multifocal or generalized lesions should prompt a thorough clinical work-up for internal neoplasia.
Elizabeth A Mauldin; Daniel O Morris; Michael H Goldschmidt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary dermatology     Volume:  13     ISSN:  0959-4493     ISO Abbreviation:  Vet. Dermatol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-03-18     Completed Date:  2002-04-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9426187     Medline TA:  Vet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  7-13     Citation Subset:  IM    
Department of Clinical Studies, Veterinary Hospital of the University of Pennsylvania, 3850 Spruce St. Philadelphia, PA 19104, USA.
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MeSH Terms
Cat Diseases / epidemiology*,  microbiology,  pathology*
Dermatomycoses / epidemiology,  pathology,  veterinary*
Malassezia / isolation & purification*
Pennsylvania / epidemiology
Records as Topic / veterinary
Retrospective Studies

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