| Retrospective study of continuation electroconvulsive therapy in 50 patients. | |
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MedLine Citation:
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PMID: 20357668 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVES: To examine patient and treatment characteristics in continuation electroconvulsive therapy (c-ECT), defined as prolonged treatment with ECT with a maximum frequency of once a week to prevent relapse. METHODS: Medical charts of 50 patients (mean age, 59 years; 74% were female) undergoing c-ECT were examined retrospectively for patient and treatment characteristics. Electrical stimulus dosage, seizure duration, and postictal suppression indices between the first and the last 4 ECT sessions were compared, and their associations with the time interval between c-ECT sessions were analyzed. RESULTS: Almost all the patients (n=46; 92%) experienced recurrent medication-resistant mood disorders. During a median c-ECT period of 393 days (interquartile rate, 211-677 days), the frequency of c-ECT ranged from once a week (n=15; 30%) to once every 4 to 6 weeks (n=17; 34%), and ECT was administered almost exclusively bifrontotemporally (n=46, 92%). The mean (SD) time interval between consecutive c-ECT sessions was 19 (11) days. The number of days between c-ECT sessions correlated positively with median seizure duration (motor activity: r=0.390, P=0.005; electroencephalographic activity: r=0.351, P=0.013). CONCLUSIONS: In 50 patients with long-standing, recurrent, medication-resistant mood disorders who were treated with c-ECT, increased time interval between consecutive c-ECT sessions was correlated with increased seizure duration. Whether bifrontotemporal c-ECT requires a lower frequency to sustain remission compared with unilateral c-ECT needs further investigation. |
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Authors:
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Jeroen A van Waarde; Dianne Wielaard; Jaap Wijkstra; Bastiaan Verwey; Rose C van der Mast |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of ECT Volume: 26 ISSN: 1533-4112 ISO Abbreviation: J ECT Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808943 Medline TA: J ECT Country: United States |
Other Details:
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Languages: eng Pagination: 299-303 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Rijnstate Hospital, Alysis Zorggroep, Arnhem, the Netherlands. jvanwaarde@alysis.nl |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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