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Retrospective study of continuation electroconvulsive therapy in 50 patients.
MedLine Citation:
PMID:  20357668     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVES: To examine patient and treatment characteristics in continuation electroconvulsive therapy (c-ECT), defined as prolonged treatment with ECT with a maximum frequency of once a week to prevent relapse.
METHODS: Medical charts of 50 patients (mean age, 59 years; 74% were female) undergoing c-ECT were examined retrospectively for patient and treatment characteristics. Electrical stimulus dosage, seizure duration, and postictal suppression indices between the first and the last 4 ECT sessions were compared, and their associations with the time interval between c-ECT sessions were analyzed.
RESULTS: Almost all the patients (n=46; 92%) experienced recurrent medication-resistant mood disorders. During a median c-ECT period of 393 days (interquartile rate, 211-677 days), the frequency of c-ECT ranged from once a week (n=15; 30%) to once every 4 to 6 weeks (n=17; 34%), and ECT was administered almost exclusively bifrontotemporally (n=46, 92%). The mean (SD) time interval between consecutive c-ECT sessions was 19 (11) days. The number of days between c-ECT sessions correlated positively with median seizure duration (motor activity: r=0.390, P=0.005; electroencephalographic activity: r=0.351, P=0.013).
CONCLUSIONS: In 50 patients with long-standing, recurrent, medication-resistant mood disorders who were treated with c-ECT, increased time interval between consecutive c-ECT sessions was correlated with increased seizure duration. Whether bifrontotemporal c-ECT requires a lower frequency to sustain remission compared with unilateral c-ECT needs further investigation.
Authors:
Jeroen A van Waarde; Dianne Wielaard; Jaap Wijkstra; Bastiaan Verwey; Rose C van der Mast
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of ECT     Volume:  26     ISSN:  1533-4112     ISO Abbreviation:  J ECT     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808943     Medline TA:  J ECT     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-303     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Rijnstate Hospital, Alysis Zorggroep, Arnhem, the Netherlands. jvanwaarde@alysis.nl
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