Document Detail

Retrospective analysis of vision correction and lens tolerance in keratoconus patients prescribed a contact lens with dual aspherical curves.
MedLine Citation:
PMID:  20145543     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine whether Aphex KC, a newly designed rigid gas-permeable (RGP) contact lens with dual aspherical base curves, improves visual acuity and lens wear time in patients with keratoconus. METHODS: We performed a retrospective analysis of a noncomparative case series of 29 eyes of 24 patients with keratoconus who were intolerant of spherical RGP contact lenses and were fitted with Aphex KC at Yamaguchi University Hospital. Visual acuity and lens wear time were recorded as primary outcome measures at follow-up visits. Six patients with a follow-up period of <1 year were excluded from data analysis. At the last follow-up visit, 86.2% of eyes (25 eyes of 20 patients) continued to wear Aphex KC. RESULTS: Mean uncorrected visual acuity was 1.4 LogMAR (20/500 in Snellen notation) for the 29 eyes enrolled in the study. Mean best-corrected visual acuity was 0.1 LogMAR (20/25) with Aphex KC and 0.7 LogMAR (20/111) with glasses (P < 0.001). A total of 19 eyes (65.5%) had a best-corrected visual acuity of 0.2 LogMAR (20/29) or better with Aphex KC. The mean +/- SD wear time was 12.6 +/- 3.2 hr/day with Aphex KC and 0.4 +/- 0.7 hr/day with a previously prescribed spherical RGP contact lens (P = 1 x 10). The numbers of eyes wearing Aphex KC or the previously prescribed RGP contact lens for >12 hr/day were 26 and 0, respectively (P = 1 x 10). No serious complications of Aphex KC wear were observed. CONCLUSIONS: Fitting of an Aphex KC lens improved visual acuity and increased lens wear time in keratoconus patients who were intolerant of a spherical RGP contact lens. Aphex KC thus provides a viable alternative for management of such patients.
Ryoji Yanai; Kiichi Ueda; Teruo Nishida
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Eye & contact lens     Volume:  36     ISSN:  1542-233X     ISO Abbreviation:  Eye Contact Lens     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160941     Medline TA:  Eye Contact Lens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-9     Citation Subset:  IM    
Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube City, Yamaguchi, Japan.
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MeSH Terms
Contact Lenses* / adverse effects
Equipment Design
Follow-Up Studies
Keratoconus / physiopathology*,  rehabilitation*
Middle Aged
Retrospective Studies
Time Factors
Visual Acuity*
Young Adult
Reg. No./Substance:

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