| Retroperitoneal nephroureterectomy with excision of cuff of the bladder for upper urinary tract transitional cell carcinoma: comparison of laparoscopic and open surgery with long-term follow-up. | |
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MedLine Citation:
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PMID: 18431579 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To compare outcome and long term follow up of laparoscopic retroperitoneal nephroureterectomy with excision of cuff of bladder (LRPNUT-BCE) and standard open nephroureterectomy with excision of cuff of bladder (ONUT-BCE) in patients of upper urinary tract transitional cell carcinoma (UTTCC). MATERIAL AND METHODS: From January 1998 to October 2006, we have performed over 55 cases of nephroureterectomy with excision of cuff of bladder for UTTCC. Out of these, 48 patients undergoing LRPNUT-BCE and ONUT-BCE were categorized retrospectively into group A (21), and group B (27), respectively. The clinical data including intraoperative, postoperative, and follow-up data was recorded for two groups and analyzed statistically. RESULTS: The mean operating time was significantly higher in-group A (P < 0.001). The different techniques of bladder cuff excision were used in group A. The mean analgesic use, hospital stay and weeks to normal activity were significantly lesser in-group A (P < 0.001). The intraoperative, postoperative complications and mean follow up were comparable in two groups. There was no local recurrence in either group. The bladder recurrence and distant metastases were comparable in two groups (group A--9.52%, group B--11.1% and group A--9.52%, group B--11.1%, respectively). The 5-year recurrence free, cancer specific and overall survivals were comparable in two groups. CONCLUSIONS: On long-term follow-up of oncological efficacy, LRPNUT-BCE satisfactorily compares with traditional open surgery (ONUT-BCE) with longer operating time, while decreasing postoperative morbidity and extending benefits of minimally invasive surgery to the patients. |
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Authors:
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Ashok K Hemal; Anup Kumar; Narmada P Gupta; Amlesh Seth |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-04-23 |
Journal Detail:
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Title: World journal of urology Volume: 26 ISSN: 0724-4983 ISO Abbreviation: World J Urol Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-18 Completed Date: 2009-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8307716 Medline TA: World J Urol Country: Germany |
Other Details:
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Languages: eng Pagination: 381-6 Citation Subset: IM |
Affiliation:
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Department of Urology, All India Institute of Medical Sciences, New Delhi, India. ahemal@wfubmc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Transitional Cell / mortality, surgery* Disease-Free Survival Female Follow-Up Studies Humans Kaplan-Meiers Estimate Laparoscopy* / mortality Male Middle Aged Neoplasm Recurrence, Local Nephrectomy / methods*, mortality Postoperative Complications Retroperitoneal Space / surgery Retrospective Studies Ureter / surgery* Urinary Bladder / surgery Urinary Bladder Neoplasms / mortality, surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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