| Retinopathy and subconjunctival haemorrhage in patients with chronic viral hepatitis receiving interferon alfa. | |
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MedLine Citation:
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PMID: 7696235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 43 patients (86 eyes) with chronic viral hepatitis were examined prospectively before and after the start of interferon therapy. Of 37 non-diabetic patients, 23 (group A1) did not have retinopathy or subconjunctival haemorrhage, 11 (group A2) developed retinopathy, and three (group A3) exhibited subconjunctival haemorrhage during the treatment. In most eyes, the retinopathy disappeared after therapy was stopped. Of six diabetic patients, three (group B1) developed retinopathy and three (group B2) showed progression of existing retinopathy. Thrombocytopenia was not associated with the retinopathy in any patient. The patients' good visual acuity remained unchanged, even after retinal changes appeared. Ophthalmologists should be aware that retinopathy and subconjunctival haemorrhage may develop in patients with chronic viral hepatitis receiving interferon therapy. |
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Authors:
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S Hayasaka; M Fujii; Y Yamamoto; S Noda; H Kurome; M Sasaki |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of ophthalmology Volume: 79 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-05-04 Completed Date: 1995-05-04 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 150-2 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, Shimane Medical University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Chronic Disease Conjunctiva Eye Hemorrhage / etiology* Female Hepatitis B / therapy* Hepatitis C / therapy* Humans Interferon Type I, Recombinant / adverse effects* Leukocyte Count Male Middle Aged Prospective Studies Retinal Diseases / etiology* |
| Chemical | |
Reg. No./Substance:
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0/Interferon Type I, Recombinant |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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