Document Detail


Retinopathy of prematurity and the oxygen conundrum: lessons learned from recent randomized trials.
MedLine Citation:
PMID:  23719307     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Emerging data from randomised controlled trials of different pulse oximeter oxygen saturation (SpO2) target ranges shows that higher SpO2 targets are associated with a higher risk of severe retinopathy of prematurity. However, the trials have also shown that higher SpO2 targets are associated with improved survival. In the light of these results and pending the full results for long-term outcome, it is recommended that oxygen saturation targets for preterm infants of gestational age less than 28 weeks at birth should be maintained at or more than 90%.
Authors:
Brian W Fleck; Ben J Stenson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in perinatology     Volume:  40     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  229-40     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Affiliation:
Department of Ophthalmology, Princess Alexandra Eye Pavilion, Chalmers Street, Edinburgh, EH3 9HA, UK. Electronic address: Brian.Fleck@ed.ac.uk.
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