Document Detail

Retinopathy of prematurity: incidence and risk factors.
MedLine Citation:
PMID:  9141799     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the incidence of Retinopathy of Prematurity (ROP) in high risk babies admitted to the neonatal unit and to study risk factors for it's development. DESIGN: Prospective cohort study. SETTING: Level II Neonatal Intensive Care Unit. SUBJECTS: 100 babies admitted to the neonatal unit during a 4 year period who were below 1500 g or whose gestation was < or = 34 weeks. METHODS: Examination of the eye was done in the neonatal unit or in the neonatal follow up clinic by an Ophthalmologist by indirect Ophthalmoscopy at 4-6 weeks postnatal age. RESULTS: The incidence of ROP was 46%. Of the 100 babies screened, 21 had stage I, 14 had stage II, 8 had stage III and 3 had stages IV and V. The incidence of ROP was 73.3% among < 1000 g babies and 47.3% among < 1500 g babies. The incidence of ROP among 28-29 weeks, 30-31 weeks and 32-33 weeks babies was 83%, 60% and 50%, respectively. The maximum stage of ROP developed between 37-42 weeks post conceptional age in 69% subjects. On univariate analysis, gestation < or = 32 weeks, anemia, Blood transfusions, apnea and exposure to oxygen significantly increased the risk of developing ROP. On multivariate logistic regression analysis, anemia and duration of oxygen therapy were the significant independent predictors of development of ROP. Nine of the 46 babies underwent cryotherapy for threshold ROP. CONCLUSION: The incidence of ROP among high risk babies is significant and duration of oxygen therapy and anemia are independent factors predicting the development of ROP. All high risk babies should be screened for ROP. Cryotherapy is a relatively simple procedure which can be done in the neonatal unit.
S Rekha; R R Battu
Related Documents :
10685989 - Severe retinopathy of prematurity and its association with different rates of survival ...
9677059 - Mosaic variegated aneuploidy with multiple congenital abnormalities: homozygosity for t...
17429909 - Mode of delivery and threshold retinopathy of prematurity in pre-term elbw neonates.
19928699 - Incidence of retinopathy of prematurity in a neonatal intensive care unit in nepal.
10081569 - 3-dimensional analysis of cleft palate casts.
6430649 - Appliance for stabilizing orogastric and orotracheal tubes in infants.
22368919 - Perception and practices of breastfeeding of infants 0-6 months in an urban and a semi-...
23253829 - Serologically determined in utero exposure to oral pathogens may be associated with inc...
2352259 - Restrictive dermopathy: a report of three cases.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian pediatrics     Volume:  33     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-29     Completed Date:  1997-05-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  999-1003     Citation Subset:  IM    
Department of Pediatrics, St. John's Medical College Hospital, Bangalore.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analysis of Variance
Anemia / epidemiology
Apnea / epidemiology
Blood Transfusion / statistics & numerical data
Cohort Studies
Follow-Up Studies
Gestational Age
India / epidemiology
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Infant, Very Low Birth Weight
Logistic Models
Multivariate Analysis
Oxygen Inhalation Therapy / statistics & numerical data
Prospective Studies
Retinopathy of Prematurity / classification,  epidemiology*,  surgery
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Our experience in the diagnostics of liver and spleen hemangiomas.
Next Document:  Hemostatic profile in nephrotic syndrome.