Document Detail

Retinopathy of prematurity in the United States.
MedLine Citation:
PMID:  18303153     Owner:  NLM     Status:  MEDLINE    
AIMS: To determine the incidence of retinopathy of prematurity (ROP) based upon a national database and to identify baseline characteristics, demographic information, comorbidities, and surgical interventions. METHODS: The National Inpatient Sample, a representative sample of all US hospital discharges from 1997 to 2002, was queried for all newborn infants with and without ROP. Primary outcome variables included demographics, comorbidities, hospital length of stay (LOS), and hospital charges. Multivariate logistic regression was used to predict risk factors for ROP. RESULTS: 4.67 million live births were recorded during the study period. The total incidence of ROP was 0.12% overall and 7.35% for premature infants with LOS greater than 14 days. Newborns with ROP were more likely to be born at a teaching hospital and to have higher LOS and hospitalisation charges. The odds ratios for the development of ROP were greatest in infants weighing less than 1250 grams. The multivariate regression model revealed that only respiratory distress and intraventricular haemorrhage were predictive of the development of ROP and Hispanic infants were 33% more likely to develop ROP. CONCLUSION: This study represents the largest cohort of newborns analysed for ROP. The multivariate analysis emphasised the role of birth weight in extended-stay infants, as well as Hispanic race, respiratory distress syndrome, and intraventricular haemorrhage.
E M Lad; T C Nguyen; J M Morton; D M Moshfeghi
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  92     ISSN:  1468-2079     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-14     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  320-5     Citation Subset:  IM    
Department of Ophthalmology, Stanford University School of Medicine, 1225 Crane Street, Menlo Park, CA 94025, USA.
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MeSH Terms
Birth Weight
Cerebral Hemorrhage / epidemiology
Epidemiologic Methods
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Laser Coagulation / utilization
Length of Stay / statistics & numerical data
Respiratory Distress Syndrome, Newborn / epidemiology
Retinopathy of Prematurity / epidemiology*,  etiology,  surgery
Scleral Buckling / utilization
United States / epidemiology
Erratum In:
Br J Ophthalmol. 2010 Sep;94(9):1268

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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