Document Detail


Retinopathy of prematurity: frequency and risk factors in a tertiary care hospital in Karachi, Pakistan.
MedLine Citation:
PMID:  18655427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: To determine the frequency of Retinopathy of Prematurity (ROP) in the premature infants born in a tertiary care hospital and to determine the risk factors associated with it. METHODS: This was a retrospective analysis of premature infants with birth weight < or = 1500 grams or gestational ago < or = 32 weeks, admitted to the Neonatal Intensive Care Unit of a tertiary care hospital in a three year period. The infants underwent eye examinations between their 4th and 7th week of life. Univariate and multiple logistic regression analysis were performed to determine the association between risk factors and ROP development. RESULTS: Sixty eight infants were included in the analysis. Out of these, 22 (32.4%) developed ROP (inclusive of all stages) and 14 (20.6%) developed threshold disease. Multiple logistic regression analysis revealed that low gestational age, sepsis and respiratory distress syndrome were independent predictors for the development of ROP. CONCLUSION: The frequency of ROP in our hospital was on the higher side of the range reported in neighbouring developing countries. Low gestational age, sepsis and respiratory distress syndrome were independent predictors of ROP development. Our results suggest that ROP is an important emerging cause of preventable childhood blindness in urban areas of Pakistan like Karachi.
Authors:
Ather M Taqui; Reema Syed; Tanveer A Chaudhry; Khabir Ahmad; Muhammad S Salat
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  58     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-07-28     Completed Date:  2008-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  186-90     Citation Subset:  IM    
Affiliation:
Department of Surgery, Aga Khan University, Karachi, Pakistan.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Incidence
Infant, Newborn
Infant, Premature
Intensive Care Units, Neonatal / statistics & numerical data
Logistic Models
Male
Pakistan / epidemiology
Retinopathy of Prematurity / epidemiology*
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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