Document Detail

Retinol deficiency and urinary stone disease: clinical evidence is missing.
MedLine Citation:
PMID:  8316814     Owner:  NLM     Status:  MEDLINE    
Serum retinol levels were studied in: (a) 95, 56 and 43 normal subjects belonging to lower, middle and upper socio-economic groups respectively, (b) 35 adult males suffering from night blindness, (c) 27 subjects with low retinol levels, (d) 8 retinol deficient subjects (e) 17 male infants suffering from overt retinol deficiency, (f) 43 radiologically confirmed stone patients and (g) age and sex matched controls (infants 20; adults 120). The subjects included in groups b to f were clinically and radiologically examined for stone disease. Some inhibitors and promotors of stone disease were estimated in urine in groups b to g. It was found that 68% of subjects in lower socioeconomic group had serum retinol levels between 10 and 19 ug%, and 4% below 10 ug%, but none of them showed any symptoms of retinol deficiency. The subjects included in groups b to e did not show any significant difference in their urine chemistry although oxalate excretion was slightly but not significantly higher in comparison to controls. None of them showed radiological evidence of urinary stones. Thus, our results do not support an association between retinol deficiency and urolithiasis in the population studied.
P P Singh; R Kiran
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scanning microscopy     Volume:  7     ISSN:  0891-7035     ISO Abbreviation:  Scanning Microsc.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-07-28     Completed Date:  1993-07-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8704616     Medline TA:  Scanning Microsc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  443-6     Citation Subset:  IM    
Department of Biochemistry, R.N.T. Medical College, Udaipur, Rajasthan, India.
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MeSH Terms
Child, Preschool
Middle Aged
Risk Factors
Urinary Calculi / etiology*,  metabolism
Vitamin A Deficiency / complications*,  metabolism

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