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Retinoids in the Chemoprevention of Non-Melanoma Skin Cancers: Why, when and How.
MedLine Citation:
PMID:  23148804     Owner:  NLM     Status:  Publisher    
Abstract The chemoprevention of non-melanoma skin cancer refers to the use of various types of chemical agents for preventing carcinogenic progression, particularly in high-risk population. Retinoids are the most studied, among the possible chemopreventive agents, due to their capacity to regulate cell proliferation and their demonstrated efficacy in several clinical studies. However neither guidelines nor approval by Food and Drugs Administration exist to regulate the use of retinoids in chemoprevention. Despite numerous studies of the literature concerning retinoids in chemoprevention of non-melanoma skin cancer, precise details of the type of retinoid to use, dosage and the duration of this preventive treatment and how to manage side effects in the case of long lasting treatment are still not uniform and comparable. The authors report a revision of available literature data.
Vincenzo Bettoli; Stefania Zauli; Anna Virgili
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-14
Journal Detail:
Title:  The Journal of dermatological treatment     Volume:  -     ISSN:  1471-1753     ISO Abbreviation:  J Dermatolog Treat     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8918133     Medline TA:  J Dermatolog Treat     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Azienda Ospedaliera Universitaria di Ferrara, Arcispedale S.Anna, Department of Clinical and Experimental Medicine , Section of Dermatology, Corso Giovecca 203, Ferrara, Italy, 44100.
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