Document Detail


Retinoic acid signalling in the development of branchial arches.
MedLine Citation:
PMID:  15380252     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Branchial arches develop through a complex sequence of interactions between migrating cells, derived from neural crest and mesoderm, and epithelia of ectodermal and endodermal origin, to yield a variety of derivatives, notably skeletal elements, arteries and glands. In all vertebrate species, dramatic malformations generated by experimental blocks or activations of retinoic acid signalling highlight key roles for this molecule in the endoderm for branchial arch formation and morphogenesis.
Authors:
Manuel Mark; Norbert B Ghyselinck; Pierre Chambon
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in genetics & development     Volume:  14     ISSN:  0959-437X     ISO Abbreviation:  Curr. Opin. Genet. Dev.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-21     Completed Date:  2005-02-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9111375     Medline TA:  Curr Opin Genet Dev     Country:  England    
Other Details:
Languages:  eng     Pagination:  591-8     Citation Subset:  IM    
Affiliation:
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut Clinique de la Souris (ICS), CNRS/INSERM/ULP, Collège de France, BP10142, 67404 Illkirch Cedex, CU de Strasbourg, France. marek@igbmc.u-strasbg.fr
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MeSH Terms
Descriptor/Qualifier:
Animals
Branchial Region / cytology,  embryology*,  metabolism*
Cell Movement
Humans
Receptors, Retinoic Acid / chemistry,  genetics,  metabolism
Signal Transduction*
Tretinoin / metabolism*
Chemical
Reg. No./Substance:
0/Receptors, Retinoic Acid; 302-79-4/Tretinoin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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