Document Detail


Retinitis pigmentosa in Puerto Rico.
MedLine Citation:
PMID:  17550097     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Previous studies have reported that the prevalence of retinitis pigmentosa (RP) varies between one per 3,000 to one in per 5,000 in the general population. PURPOSE: To study the incidence and ocular findings of RP in a sub-urban community in Puerto Rico. METHODS: We conducted a non-concurrent prospective study of 10,100 patients in a sub-urban San Juan community. RESULTS: 44 out of the 10,100 patients had RP (0.44%). Eight out of the 44 patients (18%) had nystagmus, twenty-eight (31.8%) had microcornea, 3 patients (6.8%) had sluggish papillary reaction. Six patients (13.6%) had mild cataracts, 27 (65.9%)had attenuated retinal vessels and thirty five patients (81.4%) had bony spicules. Fifteen patients (34.1%) out of the 44 had retinitis pigmentosa as part of the Bardet-Biedl syndrome. CONCLUSION: Incidence of RP in Puerto Rico is higher when compared to Maine and Spain (p < 0.001). Autosomal recessive pattern of inheritance is the most common in Puerto Rico. These findings could be due to the island's geographic isolation, and inbreeding.
Authors:
Horacio M Tous; Natalio J Izquierdo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Puerto Rico health sciences journal     Volume:  25     ISSN:  0738-0658     ISO Abbreviation:  P R Health Sci J     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-06-06     Completed Date:  2007-08-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303541     Medline TA:  P R Health Sci J     Country:  Puerto Rico    
Other Details:
Languages:  eng     Pagination:  315-8     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Child, Preschool
Female
Humans
Incidence
Male
Middle Aged
Prospective Studies
Puerto Rico / epidemiology
Retinitis Pigmentosa / epidemiology*
Suburban Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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