Document Detail

Retinal vein occlusion and the prevalence of lipoprotein abnormalities.
MedLine Citation:
PMID:  7066266     Owner:  NLM     Status:  MEDLINE    
Ninety-nine patients with retinal vein occlusion (40 with central, 59 with branch vein occlusion) were investigated for the prevalence of associated diseases for comparison with an age-matched control group. There was a significantly increased prevalence of hyperlipidaemia (p less than 0.001) and hypercholesterolaemia (p less than 0.001) in the group with branch retinal vein occlusion and of hyperlipidaemia (p less than 0.001) and hypercholesterolaemia (p less than 0.02) in the group with central retinal vein occlusion compared with controls. An increased prevalence of hypertriglyceridaemia (p less than 0.001) was also found in patients with central vein occlusion. Other associations were noted (hypertension and oestrogen therapy). Increased serum cholesterol concentrations were found in patients with central vein occlusion (p less than 0.05) and branch vein occlusion (p less than 0.001) compared with controls, and similar tendencies were noted for levels of LDL and HDL cholesterol. Patients with central vein occlusion also had raised levels of serum triglyceride (p less than 0.001) and VLDL-triglyceride (p less than 0.05). The occurrence of both central and branch vein occlusions may be associated with an increased prevalence of hyperlipidaemia and hypertension. Increase of serum lipids may contribute to the aetiology of vein occlusion by altering plasma viscosity or affecting platelet function.
P M Dodson; D J Galton; A M Hamilton; R K Blach
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  66     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1982 Mar 
Date Detail:
Created Date:  1982-06-21     Completed Date:  1982-06-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  161-4     Citation Subset:  IM    
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MeSH Terms
Constriction, Pathologic / blood,  etiology
Hypercholesterolemia / complications*
Hyperlipidemias / complications*
Lipoproteins / blood
Middle Aged
Retinal Vein*
Vascular Diseases / blood,  etiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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