Document Detail


Retinal toxicity of trace elements.
MedLine Citation:
PMID:  3508798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute toxicity of lead, nickel and cobalt on rabbit retina was studied. It was found that all these metals produced similar photoreceptor degenerative changes, but lead produced extensive degenerative changes at ganglion cell layer also. Electroretinographically nickel group showed statistically (by analysis of variance) significant prolongation of 'b' wave implicit time as seen in autosomal dominant retinitis pigmentosa.
Authors:
P K Khosla; K S Murthy; H K Tewari
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of ophthalmology     Volume:  35     ISSN:  0301-4738     ISO Abbreviation:  Indian J Ophthalmol     Publication Date:  1987  
Date Detail:
Created Date:  1989-07-12     Completed Date:  1989-07-12     Revised Date:  2008-09-03    
Medline Journal Info:
Nlm Unique ID:  0405376     Medline TA:  Indian J Ophthalmol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  311-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cobalt / toxicity
Lead / toxicity
Nickel / toxicity
Rabbits
Retina / drug effects*
Trace Elements / toxicity*
Chemical
Reg. No./Substance:
0/Trace Elements; 7439-92-1/Lead; 7440-02-0/Nickel; 7440-48-4/Cobalt

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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