Document Detail


Retinal pigment epithelial degeneration, partial retinal atrophy and macular hole in acute lymphocytic leukemia.
MedLine Citation:
PMID:  1079418     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A seven year old child with acute lymphocytic leukemia presented at autopsy with a macular hole, and degeneration of the retinal pigment epithelium and its overlying photoreceptors. She had been treated with cobalt 60, methotrexate, vincristine cyclophosphamide and prednisone. A review of the literature of similar findings as well as pigment epithelial degenerations from other causes is presented.
Authors:
D M Inkeles; A H Friedman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology     Volume:  194     ISSN:  0065-6100     ISO Abbreviation:  Albrecht Von Graefes Arch Klin Exp Ophthalmol     Publication Date:  1975  
Date Detail:
Created Date:  1975-07-28     Completed Date:  1975-07-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0044637     Medline TA:  Albrecht Von Graefes Arch Klin Exp Ophthalmol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  253-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use
Atrophy
Child
Choroid / pathology
Epithelium
Female
Humans
Leukemia, Lymphoid / complications*,  drug therapy
Macular Degeneration / etiology
Optic Nerve / pathology
Photoreceptor Cells
Retinal Degeneration / etiology*
Retinal Pigments
Retinal Vessels / pathology
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Retinal Pigments

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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