| Retinal function in patients with serpiginous choroiditis: a microperimetry study. | |
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MedLine Citation:
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PMID: 20464557 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To investigate fixation pattern and retinal sensitivity in patients with serpiginous choroiditis (SC). METHODS: Twenty-eight eyes (14 patients) with SC were evaluated. Best-corrected visual acuity, color fundus photography, fundus autofluorescence, and fluorescein and indocyanine green angiography were performed. Microperimetry was used to assess fixation pattern and retinal sensitivity. RESULTS: Of 28 eyes, 16 (57%) had central, one (4%) poor central, and 11 (39%) eccentric fixation; and 18 (64%) had stable, four (14%) relatively unstable, and six (21%) unstable fixation. In patients with posterior pole symmetrically involved in both eyes, the better eye had stable and central fixation in all cases. Atrophic lesions were characterized by a dense scotoma in all cases, with a relative scotoma at their margins in ten eyes (38%). In two cases of active disease, a dense scotoma correlated to an active lesion could be detected. A relative scotoma was documented in areas not involved by the disease at the posterior pole in eight eyes (28%), and in the peripapillary area in 11 eyes (39%). CONCLUSIONS: Quantification of retinal sensitivity and fixation pattern by microperimetry offers new data about the impact of visual impairment in patients with SC. A reduction of retinal sensitivity in an apparently healthy area suggests a wider functional involvement of the retina, undetectable by morphologic evaluation alone. |
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Authors:
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Elisabetta Pilotto; Stela Vujosevic; Vuga Ana Grgic; Patrik Sportiello; Enrica Convento; Antonio Giovanni Secchi; Edoardo Midena |
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Publication Detail:
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Type: Journal Article Date: 2010-05-13 |
Journal Detail:
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Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Volume: 248 ISSN: 1435-702X ISO Abbreviation: Graefes Arch. Clin. Exp. Ophthalmol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-07-27 Completed Date: 2010-09-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8205248 Medline TA: Graefes Arch Clin Exp Ophthalmol Country: Germany |
Other Details:
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Languages: eng Pagination: 1331-7 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Padova, via Giustiniani 2, Padua, Italy. elisabetta.pilotto@unipd.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Choroiditis
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diagnosis,
physiopathology* Coloring Agents / diagnostic use Fixation, Ocular / physiology Fluorescein Angiography Humans Indocyanine Green / diagnostic use Male Middle Aged Perimetry* Retina / physiopathology* Scotoma / diagnosis, physiopathology Visual Acuity / physiology |
| Chemical | |
Reg. No./Substance:
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0/Coloring Agents; 3599-32-4/Indocyanine Green |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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