Document Detail

Retinal detachment and herpesvirus retinitis in patients with AIDS.
MedLine Citation:
PMID:  7626574     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The prolongation of survival of patients with herpesvirus retinitis and AIDS has been associated with a rise in the incidence of retinal detachment. In such cases, however, retinal reattachment may be difficult to achieve, and postoperative visual acuity may be poor despite anatomically successful surgery. METHODS: In order to examine factors affecting the visual outcome of surgery, a retrospective review of 29 patients with retinal detachment, herpesvirus retinitis, and AIDS was performed. Retinal reattachment surgery (32 procedures) or prophylactic laser demarcation (five procedures) was performed in 28 eyes of 23 patients. RESULTS: The macula was attached in 23/28 (82%) eyes at the last outpatient visit. Best postoperative visual acuity (median 6/18, range 6/6-hand movements) was significantly greater than final postoperative acuity (median counting fingers, range 6/6-no perception of light) (Wilcoxon sign rank test, p = 0.003), and was retained for a median of 3 months (1-91 weeks) after surgery. Poor visual outcome as evidenced by submedian final visual acuity was invariably associated with persistence of macular detachment, and significantly associated with the occurrence of optic atrophy (odds ratio = 5, p = 0.02). CONCLUSION: Retinal reattachment surgery appears justified in patients with herpesvirus retinitis and AIDS, but postoperative visual deterioration may occur in association with optic atrophy.
J G Dowler; H M Towler; S M Mitchell; R J Cooling; S L Lightman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  79     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-09-07     Completed Date:  1995-09-07     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  575-80     Citation Subset:  IM; X    
Moorfields Eye Hospital, London.
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MeSH Terms
AIDS-Related Opportunistic Infections / complications*
Acquired Immunodeficiency Syndrome / complications*
Herpes Zoster Ophthalmicus / complications*
Middle Aged
Postoperative Period
Retinal Detachment / physiopathology,  surgery,  virology*
Retinitis / complications*
Retrospective Studies
Treatment Outcome
Visual Acuity
Grant Support
//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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