Document Detail

Retinal circulation in primary open-angle glaucoma tested by videodensitometric image analysis.
MedLine Citation:
PMID:  1514747     Owner:  NLM     Status:  MEDLINE    
To investigate the retinal circulation in primary open-angle glaucoma (POAG), we used videodensitometric image analysis of fluorescein angiography to calculate the build-up time, the time constant of the washout rate, and the mean circulation time (MCT) in both the retinal artery and vein. We found the MCT in the POAG group (23 eyes of 20 patients) was significantly longer than in the normal group (3.7 +/- 2.0 sec and 2.8 +/- 1.7 sec, respectively; P less than .05). It correlated significantly with the vertical cup-to-disc ratio (r = .32; P less than .01), the outflow facility (r = -.35, P less than .005), and the glaucomatous visual-field loss. There was no correlation between MCT and intraocular pressure tested at the same time (r = .09, not significant). Therefore, treatment to decrease the intraocular pressure may not be associated directly with improved retinal circulation.
R Suzuki; I Sugihara; S Kurimoto
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of ophthalmology     Volume:  24     ISSN:  0003-4886     ISO Abbreviation:  Ann Ophthalmol     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-10-01     Completed Date:  1992-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0210137     Medline TA:  Ann Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  273-7     Citation Subset:  IM    
Department of Ophthalmology, Yamaguchi University School of Medicine, Ube City, Japan.
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MeSH Terms
Fluorescein Angiography
Glaucoma, Open-Angle / diagnosis*,  physiopathology
Image Processing, Computer-Assisted
Intraocular Pressure
Middle Aged
Regional Blood Flow
Retinal Vessels / physiopathology*
Visual Fields

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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