| Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography. | |
| | |
MedLine Citation:
|
PMID: 19279309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: Morphologic changes in the retina and choroid are closely related with high myopia-related diseases. This study was conducted to evaluate the morphologic characteristics of normal highly myopic eyes. METHODS: Thirty-one phakic highly myopic eyes with no posterior abnormalities (18 patients; mean +/- SD age, 51.7 +/- 11.4 years) were enrolled. Retinal-choroidal thickness at the fovea 1.5 mm superiorly, inferiorly, nasally, and temporally and the choroidal curvature were measured in the 512 x 128 three-dimensional scan mode with spectral-domain optical coherence tomography. The degree of posterior staphyloma was determined as the sum of the vertical distance from the retinal pigment epithelial line beneath the fovea to the nasal, temporal, superior, and inferior edge of the image, including the fovea. The association of clinical data with these parameters was evaluated. RESULTS: The mean +/- SD central retinal thickness was 200.9 +/- 39.3 microm. The mean choroidal thickness at the fovea (100.5 +/- 56.9 microm) was significantly different from the temporal (125.4 +/- 59.7 microm), nasal (81.9 +/- 35.0 microm), and superior (129.4 +/- 57.5 microm) thicknesses (P < 0.01). Central retinal thickness did not correlate with age, sex, refractive error, axial length, or central choroidal thickness. Central choroidal thickness was significantly associated with refractive error (P < 0.05) and posterior staphyloma height (P < 0.01). Posterior staphyloma height was significantly correlated with refractive error and axial length (P < 0.01). Stepwise analysis indicated that choroidal thickness correlated significantly with age and posterior staphyloma height (P < 0.01). CONCLUSIONS: Posterior staphyloma formation was a key factor in choroidal thinning in highly myopic eyes. Choroidal thickness had a greater effect than retinal thickness in highly myopic eyes. |
| | |
Authors:
|
Yasushi Ikuno; Yasuo Tano |
Related Documents
:
|
18436839 - Increased-resolution oct thickness mapping of the human macula: a statistically based r... 16303469 - Lens prism in rgp manufacturing and its effect on edge quality. 18056739 - An investigation of the retinal nerve fibre layer in progressive multiple sclerosis usi... 20213479 - Comparison of optic nerve head topography findings in eyes with non-arteritic anterior ... 19232559 - A pilot study of enhanced depth imaging optical coherence tomography of the choroid in ... 407349 - Henneguya episclera sp. n. (protozoa: myxosporida), a new myxosporidan from the eye of ... 12102129 - Melanin bleaching in argyrophilic staining of agnors in pigmented lesions: a morphometr... 309259 - Inotropic effects of calcitonin in man. 627879 - Prismatically induced eye strain and autokinetic direction frequency. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-03-11 |
Journal Detail:
|
Title: Investigative ophthalmology & visual science Volume: 50 ISSN: 1552-5783 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 2009 Aug |
Date Detail:
|
Created Date: 2009-07-29 Completed Date: 2009-08-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: United States |
Other Details:
|
Languages: eng Pagination: 3876-80 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Osaka University Medical School, Osaka Japan. ikuno@ophthal.med.osaka-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Biometry Body Weights and Measures Choroid / pathology* Dilatation, Pathologic Female Humans Male Middle Aged Myopia, Degenerative / diagnosis* Retina / pathology* Scleral Diseases / diagnosis Tomography, Optical Coherence / methods* Visual Acuity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Myopia and polymorphisms in genes for matrix metalloproteinases.
Next Document: Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia.