Document Detail

Retinal arterial wall plaques in Susac syndrome.
MedLine Citation:
PMID:  12654364     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To demonstrate retinal arterial wall plaques (RAWPs) in patients with Susac syndrome, a disorder that consists of the triad of branch retinal artery occlusion, encephalopathy, and hearing loss. The clinician may misinterpret these RAWPs as emboli. DESIGN: Observational case series. METHODS: Four patients (one man and three women, aged 21-38 years) were examined and followed. RESULTS: Four patients with Susac syndrome had RAWPs in association with branch retinal artery occlusions. They were present in six of eight eyes. The plaques were yellow to yellow-white and located usually away from retinal bifurcations. Retinal arterial wall plaques occur at the midarteriolar segments, whereas Hollenhorst plaques occur at vascular bifurcations. Four of six eyes had resolution of the plaques. CONCLUSIONS: Retinal arterial wall plaques may occur with branch retinal artery occlusions in Susac syndrome. This finding should help the clinician who is struggling to make a diagnosis in a patient with an enigmatic encephalopathy and/or hearing loss. These plaques may resolve over time.
Robert A Egan; Thuy Ha Nguyen; J Donald M Gass; Joseph F Rizzo; John Tivnan; John O Susac
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  135     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-03-25     Completed Date:  2003-04-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  483-6     Citation Subset:  AIM; IM    
Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon, USA.
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MeSH Terms
Arteriosclerosis / diagnosis*,  physiopathology
Brain Diseases / diagnosis*,  physiopathology
Cerebrovascular Disorders / diagnosis,  physiopathology
Cochlea / blood supply
Hearing Loss, Sensorineural / diagnosis*,  physiopathology
Retinal Artery / pathology*
Retinal Artery Occlusion / diagnosis*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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