| Retinal Video Recording A New Way to Image and Diagnose Diabetic Retinopathy. | |
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MedLine Citation:
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PMID: 21684608 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To validate the use of retinal video recording for diabetic retinopathy screening by comparing with standard retinal photography and slit-lamp examination. DESIGN: Evaluation of a new diagnostic technique. PARTICIPANTS: One hundred patients. METHODS: All fundus images were captured using standard retinal still photography (FF 450 plus; Carl Zeiss) and retinal video (EyeScan; Ophthalmic Imaging System, Sacramento, CA), followed by a gold standard slit-lamp biomicroscopy examination. All videos and still images were de-identified, randomized, and interpreted by 2 senior consultant ophthalmologists (M.L.T-K. and L.L.). Kappa statistics, sensitivity, and specificity for all the diabetic retinopathy signs and grades were calculated with reference to slit-lamp examination results as the gold standard. MAIN OUTCOME MEASURES: Sensitivity and specificity of video recording for detecting diabetic retinopathy signs and grades. RESULTS: The mean age (±standard deviation [SD]) of participants was 52.8±15.1 years, mean duration of diabetes (±SD) was 13.7±9.7 years, and the mean glycosylated hemoglobin level was 8.0±1.7%. Compared with the gold standard slit-lamp examination results, the sensitivity and specificity of video recording for detecting the presence of any diabetic retinopathy was 93.8% and 99.2%, respectively (ophthalmologist 1), and 93.3% and 95.2%, respectively (ophthalmologist 2). In contrast, the sensitivity and specificity of retinal photography was 91.8% and 98.4%, respectively (ophthalmologist 1), and 92.1% and 96.8%, respectively (ophthalmologist 2), for detection of any diabetic retinopathy. Both imaging methods had 100% sensitivity and specificity in detecting sight-threatening diabetic retinopathy. For overall diabetic retinopathy grading by both ophthalmologists, the measurements of agreement (Cohen's κ coefficient) between the overall grading obtained from the retinal video versus slit-lamp examination and retinal photography versus slit-lamp examination were more than 0.90. Technical failure rate for retinal video recording and retinal photography were 7.0% and 5.5%, respectively. CONCLUSIONS: This study demonstrated that retinal video recording was equally as effective as retinal photography in the subjects evaluated in this study. It is a novel alternative diabetic retinopathy screening technique that not only offers primary eye care providers the opportunity to view numerous retinal fields within a short period but also is easy to learn by nonexperienced personnel with minimal training. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references. |
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Authors:
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Daniel S W Ting; Mei Ling Tay-Kearney; Ian Constable; Liam Lim; David B Preen; Yogesan Kanagasingam |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-17 |
Journal Detail:
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Title: Ophthalmology Volume: - ISSN: 1549-4713 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Center for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Nedlands, Australia; The Australian E-Health Research Center, Commonwealth Scientific Industrial Research Organization (CSIRO), Floreat, Australia; Ophthalmology Department, Royal Perth Hospital, Perth, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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